The Antiangiogenic Activity of rPAI-123 Inhibits Vasa Vasorum and Growth of Atherosclerotic Plaque

Plaque vascularity has been implicated in its growth and stability. However, there is a paucity of information regarding the origin of plaque vasculature and the role of vasa vasorum in plaque growth. To inhibit growth of vasa vasorum in atherogenic mice and assess its effect on plaque growth, we us...

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Veröffentlicht in:	Circulation research 2009-02, Vol.104 (3), p.337-345
Hauptverfasser:	Drinane, Mary, Mollmark, Jessica, Zagorchev, Lyubomir, Moodie, Karen, Sun, Baiming, Hall, Amy, Shipman, Samantha, Morganelli, Peter, Simons, Michael, Mulligan-Kehoe, Mary Jo
Format:	Artikel
Sprache:	eng
Schlagworte:	Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Fundamental and applied biological sciences. Psychology Medical sciences Vertebrates: cardiovascular system
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