Effects of a Black Raspberry Diet on Gene Expression in the Rat Esophagus

A diet containing 5% freeze-dried black raspberries (BRB) markedly inhibits esophageal cancer in rats treated with the carcinogen, N-Nitrosomethylbenzylamine (NMBA). We previously identified esophageal genes that become dysregulated after short-term treatment of rats with NMBA and determined which g...

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Veröffentlicht in:	Nutrition and cancer 2008-01, Vol.60 (sup1), p.61-69
Hauptverfasser:	Lechner, John F, Reen, Rashmeet K, Dombkowski, Alan A, Cukovic, Daniela, Salagrama, Sridevi, Wang, Li-Shu, Stoner, Gary D
Format:	Artikel
Sprache:	eng
Schlagworte:	animal disease models Animals anticarcinogenic activity apoptosis Biological and medical sciences carcinogens chemical constituents of plants Diet esophageal neoplasms esophagus Esophagus - drug effects Esophagus - metabolism Esophagus - pathology Feeding. Feeding behavior fruit extracts Fundamental and applied biological sciences. Psychology Gene Expression Regulation - drug effects histopathology Male microarray technology N-nitrosodimethylamine nutrition-genotype interaction nutritional intervention Oligonucleotide Array Sequence Analysis polyphenols raspberries Rats Rats, Inbred F344 Rosaceae signal transduction small fruits Transcription, Genetic - drug effects Vertebrates: anatomy and physiology, studies on body, several organs or systems
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