The Absorption of 99mTc-alendronate Given by Rectal Route in Rabbits

Alendronate sodium (ALD) is a bisphosphonate medication used in the treatment and prevention of osteoporosis. Absorption of ALD as oral formulation is very poor (0.5%-1%). Its bioavailability can decrease with food effect. It has some gastrointestinal adverse effects such as gastritis, gastric ulcer...

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Veröffentlicht in:	Pharmaceutical development and technology 2008-05, Vol.13 (3), p.213-220
Hauptverfasser:	A ko lu, Makbule, Özgüney, I k, Özcan, pek, Örümlü, Oya, Güneri, Tamer, Köseo lu, Kamil, Özk l ç, Hayal
Format:	Artikel
Sprache:	eng
Schlagworte:	alendronate sodium Biological and medical sciences General pharmacology in vitro release Medical sciences PEG 1500 Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments radiolabeling rectal absorption technetium-99m
Online-Zugang:	Volltext
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