Synthesis of the lipid peroxidation product 4-hydroxy-2(E)-nonenal with 13C stable isotope incorporation

The aim of this work was to synthesize 13C internal standards for the quantification of 4‐hydroxy‐2(E)‐nonenal (HNE), a lipid peroxidation product, and of the etheno‐adducts possibly formed by HNE damage to DNA nucleobases. We designed an eight‐step synthesis starting from ethyl 2‐bromoacetate and g...

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Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2008-02, Vol.51 (2), p.87-92
Hauptverfasser:	Jouanin, I., Sreevani, V., Rathahao, E., Guéraud, F., Paris, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	4-hydroxy-2(E)-nonenal Aliphatic compounds carbon 13 Chemistry Exact sciences and technology HNE lipid peroxidation Organic chemistry Preparations and properties synthesis
Online-Zugang:	Volltext
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