Nod-like receptors in innate immunity and inflammatory diseases

Over the past few years the field of innate immunity has undergone a revolution with the discovery of pattern recognition molecules (PRM) and their role in microbe detection. Among these molecules, the Nod-like receptors (NLRs) have emerged as key microbial sensors that participate in the global imm...

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Veröffentlicht in:	Annals of medicine (Helsinki) 2007, Vol.39 (8), p.581-593
Hauptverfasser:	Carneiro, Leticia A. M., Travassos, Leonardo H., Girardin, Stephen E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Regulatory Proteins - immunology bacterial infections Biological and medical sciences Calcium-Binding Proteins - immunology CARD Signaling Adaptor Proteins - immunology CARD Signaling Adaptor Proteins - physiology Carrier Proteins - immunology Enzyme Inhibitors - immunology General aspects Humans Immunity, Innate - physiology inflammation Inflammation - immunology inflammatory disorders innate immunity Medical sciences Neuronal Apoptosis-Inhibitory Protein - immunology NF-kappa B - immunology NLR Family, Pyrin Domain-Containing 3 Protein Nod-like Receptors Nod1 Signaling Adaptor Protein - immunology Nod2 Signaling Adaptor Protein - immunology
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