Formation of DNA triplexes accounts for arrests of DNA synthesis at d(TC)n and d(GA)n tracts

To study the mechanism of arrest of DNA synthesis at d(TC)n and d(GA)n sequences, single-stranded DNA molecules including d(TC)27 or d(TC)31 tracts or a d(GA)27 tract were used as templates for in vitro assays of complementary DNA synthesis performed by extension of a primer with the Klenow polymera...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1991-01, Vol.88 (2), p.507-511
Hauptverfasser:	BARAN, N, LAPIDOT, A, MANOR, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Base Sequence Biological and medical sciences DNA Replication DNA, Single-Stranded - biosynthesis DNA-Binding Proteins - metabolism DNA-Directed DNA Polymerase - metabolism Escherichia coli - metabolism Fundamental and applied biological sciences. Psychology Guanine - analogs & derivatives Hydrogen Bonding Kinetics Models, Structural Molecular and cellular biology Molecular genetics Molecular Sequence Data Nucleic Acid Conformation Polydeoxyribonucleotides Polymerase Chain Reaction Replication Templates, Genetic Thermodynamics
Online-Zugang:	Volltext
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