Purification of A Suppressor Lymphokine (SL) from a Human T-Cell Line

Human T leukemia cell line 81-66-45 spontaneously releases into the medium a suppressor lymphokine (SL), able to inhibit PHA-stimulated normal peripheral blood T cell proliferation. Ion exchange and gel filtration chromatography were used successfully to isolate and purify this immunosuppressive lym...

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Veröffentlicht in:	Immunological investigations 1989-01, Vol.18 (6), p.741-751
Hauptverfasser:	Abolhassani, Mohsen, Muraki, Junro, Chiao, Jen Wei
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis of the immune response. Humoral and cellular immunity Biological and medical sciences Chromatography, Ion Exchange Electrophoresis, Polyacrylamide Gel Enzyme Stability Fundamental and applied biological sciences. Psychology Fundamental immunology Humans Immunobiology Leukemia, T-Cell Lymphocytes - analysis Lymphokines - isolation & purification Lymphokines, interleukins ( function, expression) Regulatory factors and their cellular receptors Suppressor Factors, Immunologic - isolation & purification Tumor Cells, Cultured
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