Isoniazid Bactericidal Activity and Resistance Emergence: Integrating Pharmacodynamics and Pharmacogenomics To Predict Efficacy in Different Ethnic Populations
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Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2007-07, Vol.51 (7), p.2329-2336 |
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creator | GUMBO, Tawanda LOUIE, Arnold WEIGUO LIU BROWN, David AMBROSE, Paul G BHAVNANI, Sujata M DRUSANO, George L |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/AAC.00185-07</identifier><identifier>PMID: 17438043</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antitubercular Agents ; Antitubercular Agents - pharmacokinetics ; Antitubercular Agents - pharmacology ; Area Under Curve ; Bacteria ; Biological and medical sciences ; Colony Count, Microbial ; Computer Simulation ; Dose-Response Relationship, Drug ; Drug Resistance, Bacterial ; Drug Resistance, Bacterial - genetics ; Ethnic Groups ; Ethnic Groups - classification ; Humans ; Isoniazid ; Isoniazid - pharmacokinetics ; Isoniazid - pharmacology ; Medical sciences ; Microbial Sensitivity Tests ; Models, Biological ; Monte Carlo Method ; Mutation ; Mycobacterium tuberculosis ; Mycobacterium tuberculosis - drug effects ; Mycobacterium tuberculosis - genetics ; Mycobacterium tuberculosis - isolation & purification ; Pharmacogenetics ; Pharmacology ; Pharmacology. Drug treatments ; Time Factors</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2329-2336</ispartof><rights>2007 INIST-CNRS</rights><rights>Copyright © 2007 American Society for Microbiology</rights><rights>Copyright © 2007, American Society for Microbiology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a503t-27af76446431f6810cd48d44f2626cccbb4a1cec8ca10a740fd8fd076fc4b8743</citedby><cites>FETCH-LOGICAL-a503t-27af76446431f6810cd48d44f2626cccbb4a1cec8ca10a740fd8fd076fc4b8743</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913269/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913269/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,315,728,781,785,886,27929,27930,53796,53798</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18893990$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17438043$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>GUMBO, Tawanda</creatorcontrib><creatorcontrib>LOUIE, Arnold</creatorcontrib><creatorcontrib>WEIGUO LIU</creatorcontrib><creatorcontrib>BROWN, David</creatorcontrib><creatorcontrib>AMBROSE, Paul G</creatorcontrib><creatorcontrib>BHAVNANI, Sujata M</creatorcontrib><creatorcontrib>DRUSANO, George L</creatorcontrib><title>Isoniazid Bactericidal Activity and Resistance Emergence: Integrating Pharmacodynamics and Pharmacogenomics To Predict Efficacy in Different Ethnic Populations</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antitubercular Agents</subject><subject>Antitubercular Agents - pharmacokinetics</subject><subject>Antitubercular Agents - pharmacology</subject><subject>Area Under Curve</subject><subject>Bacteria</subject><subject>Biological and medical sciences</subject><subject>Colony Count, Microbial</subject><subject>Computer Simulation</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Resistance, Bacterial</subject><subject>Drug Resistance, Bacterial - genetics</subject><subject>Ethnic Groups</subject><subject>Ethnic Groups - classification</subject><subject>Humans</subject><subject>Isoniazid</subject><subject>Isoniazid - pharmacokinetics</subject><subject>Isoniazid - pharmacology</subject><subject>Medical sciences</subject><subject>Microbial Sensitivity Tests</subject><subject>Models, Biological</subject><subject>Monte Carlo Method</subject><subject>Mutation</subject><subject>Mycobacterium tuberculosis</subject><subject>Mycobacterium tuberculosis - drug effects</subject><subject>Mycobacterium tuberculosis - genetics</subject><subject>Mycobacterium tuberculosis - isolation & purification</subject><subject>Pharmacogenetics</subject><subject>Pharmacology</subject><subject>Pharmacology. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antitubercular Agents</topic><topic>Antitubercular Agents - pharmacokinetics</topic><topic>Antitubercular Agents - pharmacology</topic><topic>Area Under Curve</topic><topic>Bacteria</topic><topic>Biological and medical sciences</topic><topic>Colony Count, Microbial</topic><topic>Computer Simulation</topic><topic>Dose-Response Relationship, Drug</topic><topic>Drug Resistance, Bacterial</topic><topic>Drug Resistance, Bacterial - genetics</topic><topic>Ethnic Groups</topic><topic>Ethnic Groups - classification</topic><topic>Humans</topic><topic>Isoniazid</topic><topic>Isoniazid - pharmacokinetics</topic><topic>Isoniazid - pharmacology</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Models, Biological</topic><topic>Monte Carlo Method</topic><topic>Mutation</topic><topic>Mycobacterium tuberculosis</topic><topic>Mycobacterium tuberculosis - drug effects</topic><topic>Mycobacterium tuberculosis - genetics</topic><topic>Mycobacterium tuberculosis - isolation & purification</topic><topic>Pharmacogenetics</topic><topic>Pharmacology</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>17438043</pmid><doi>10.1128/AAC.00185-07</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
subjects | Antibiotics. Antiinfectious agents. Antiparasitic agents Antitubercular Agents Antitubercular Agents - pharmacokinetics Antitubercular Agents - pharmacology Area Under Curve Bacteria Biological and medical sciences Colony Count, Microbial Computer Simulation Dose-Response Relationship, Drug Drug Resistance, Bacterial Drug Resistance, Bacterial - genetics Ethnic Groups Ethnic Groups - classification Humans Isoniazid Isoniazid - pharmacokinetics Isoniazid - pharmacology Medical sciences Microbial Sensitivity Tests Models, Biological Monte Carlo Method Mutation Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - genetics Mycobacterium tuberculosis - isolation & purification Pharmacogenetics Pharmacology Pharmacology. Drug treatments Time Factors |
title | Isoniazid Bactericidal Activity and Resistance Emergence: Integrating Pharmacodynamics and Pharmacogenomics To Predict Efficacy in Different Ethnic Populations |
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