Epidermal Growth Factor Receptor in Cultured Human Retinal Pigment Epithelial Cells

Background: Migration and proliferation of retinal pigment epithelial (RPE) cells play an important role in proliferative vitreoretinopathy. Epidermal growth factor receptor (EGFR) is a cell surface receptor with intrinsic tyrosine kinase activity. The engagement of the receptor by its ligand can in...

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Veröffentlicht in:	Ophthalmologica (Basel) 2007-01, Vol.221 (4), p.244-250
Hauptverfasser:	Yan, Feng, Hui, Yan-nian, Li, Yang-jun, Guo, Chang-mei, Meng, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Movement - drug effects Cell Proliferation - drug effects Cells, Cultured Dose-Response Relationship, Drug Epidermal Growth Factor - pharmacology Humans Immunoenzyme Techniques In Situ Hybridization Medical sciences Miscellaneous Mitogen-Activated Protein Kinases - metabolism Ophthalmology Original Paper Phosphorylation Pigment Epithelium of Eye - cytology Pigment Epithelium of Eye - drug effects Pigment Epithelium of Eye - metabolism Receptor, Epidermal Growth Factor - genetics Receptor, Epidermal Growth Factor - metabolism Retinopathies RNA, Messenger - metabolism Signal Transduction Vitreoretinopathy, Proliferative - metabolism
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