Nitric Oxide Regulates Expression of Sonic Hedgehog and Hypoxia-Inducible Factor-1α in an Experimental Model of Kidney Ischemia-Reperfusion

This study was designed to determine the effect of L-arginine on hypoxia inducible factor alpha (HIF-1 α) and Sonic hedgehog (Shh) levels considered to be involved in the development of ischemia reperfusion (I R) injury. Unilaterally nephrectomized Sprague-Dawley rats were subjected to 60 minutes of...

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Veröffentlicht in:	Renal failure 2007-01, Vol.29 (3), p.249-256
Hauptverfasser:	Ozturk, Hayrettin, Tuncer, Mehmet Cudi, Ozturk, Hulya, Buyukbayram, Hüseyin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences hypoxia inducible factor alpha (HIF-1a) ischemia/reperfusion injury Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure renal/kidney Renovascular diseases sonic hedgehog (Shh)
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