Distinctly different sensitivity in the induction and reversal of anergy of Th1 and Th2 cells

T cell anergy is one of the mechanisms of immunological tolerance. We examined in this study the distinct responses of Th1 and Th2 cells to in vitro anergic stimulation using Th1 and Th2 cells from two strains of T cell receptor transgenic mice. Proliferation of the Th2 cells was difficult to suppre...

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Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2007-01, Vol.71 (1), p.130-137
Hauptverfasser:	Ebihara, M.(Tokyo Univ. of Agriculture and Technology, Fuchu (Japan)), Hattori, M, Yoshida, T
Format:	Artikel
Sprache:	eng
Schlagworte:	anergy Animals Biological and medical sciences Cell Proliferation CELLS Cells, Cultured CELLULE CELULAS cytokine Cytokines - biosynthesis Female Fundamental and applied biological sciences. Psychology IMMUNE RESPONSE IMMUNITE IMMUNITY IMMUNOSTIMULATION IN VITRO INMUNIDAD INMUNOESTIMULACION INTERLEUKINE INTERLEUKINS INTERLEUQUINAS MICE Mice, Inbred BALB C Mice, Transgenic ORGANISME TRANSGENIQUE proliferation RATON Receptors, Antigen, T-Cell - genetics Receptors, Antigen, T-Cell - metabolism REDUCCION REDUCTION REPONSE IMMUNITAIRE RESPUESTA INMUNOLOGICA Sensitivity and Specificity SOURIS T cell receptor (TCR)-transgenic mice Th1 Cells - cytology Th1 Cells - immunology Th1 Cells - metabolism Th1/Th2 Th2 Cells - cytology Th2 Cells - immunology Th2 Cells - metabolism TRANSGENICOS TRANSGENICS VARIEDADES VARIETE VARIETIES
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