Patterns of Metabolic Progression to Type 1 Diabetes in the Diabetes Prevention Trial-Type 1

OBJECTIVE:--There is little information regarding the pattern of metabolic deterioration before the onset of type 1 diabetes. The goal of this study was to utilize data from the Diabetes Prevention Trial-Type 1 (DPT-1) to obtain a picture of the metabolic progression to type 1 diabetes over a period...

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Veröffentlicht in:	Diabetes care 2006-03, Vol.29 (3), p.643-649
Hauptverfasser:	Sosenko, Jay M, Palmer, Jerry P, Greenbaum, Carla J, Mahon, Jeffrey, Cowie, Catherine, Krischer, Jeffrey P, Chase, H. Peter, White, Neil H, Buckingham, Bruce, Herold, Kevan C, Cuthbertson, David, Skyler, Jay S
Format:	Artikel
Sprache:	eng
Schlagworte:	Area Under Curve Biological and medical sciences Blood Glucose - metabolism C-Peptide - blood Clinical trials Development and progression Diabetes Diabetes Mellitus, Type 1 - etiology Diabetes Mellitus, Type 1 - metabolism Diabetes Mellitus, Type 1 - prevention & control Diabetes. Impaired glucose tolerance Diagnosis Disease control Disease Progression Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Glucose Glucose Tolerance Test Humans Insulin-Secreting Cells - physiology Medical sciences Peptides Prediabetic State - metabolism Risk factors Type 1 diabetes
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