Matrix GLA Protein Gene Polymorphisms: Clinical Correlates and Cardiovascular Mortality in Chronic Kidney Disease Patients

Background: Increased vascular calcification plays an important role in the pathogenesis of cardiovascular events in chronic kidney disease (CKD) patients. It is the result of an active ossification process counteracted by ‘protective’ proteins, such as matrix GLA protein (MGP). Polymorphisms of MGP...

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Veröffentlicht in:	American journal of nephrology 2005-11, Vol.25 (6), p.548-552
Hauptverfasser:	Brancaccio, Diego, Biondi, Maria Luisa, Gallieni, Maurizio, Turri, Olivia, Galassi, Andrea, Cecchini, Federica, Russo, Domenico, Andreucci, Vittorio, Cozzolino, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Calcinosis - etiology Calcium-Binding Proteins - genetics Cardiovascular Diseases - etiology Case-Control Studies Emergency and intensive care: renal failure. Dialysis management Extracellular Matrix Proteins - genetics Female Genotype Humans Intensive care medicine Kidney Failure, Chronic - complications Kidney Failure, Chronic - genetics Kidney Failure, Chronic - therapy Male Matrix Gla Protein Medical sciences Middle Aged Nephrology. Urinary tract diseases Original Report: Laboratory Investigation Polymorphism, Genetic Prospective Studies Renal Dialysis
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