Infiltrative Breast Cancer during Pregnancy and Conservative Surgery
Mastectomy is considered as the standard therapy for gestational breast cancer. Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, re...
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Veröffentlicht in: | Fetal diagnosis and therapy 2005-09, Vol.20 (5), p.442-444 |
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creator | Annane, Kadour Bellocq, Jean-Pierre Brettes, Jean-Philippe Mathelin, Carole |
description | Mastectomy is considered as the standard therapy for gestational breast cancer. Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, respectively. No local recurrences occurred with a median follow-up time of 87 months. Among the 10 patients treated with conservative surgery, 3 chose therapeutic abortion and 7 opted to continue their pregnancy. Concerning these 7 fetuses, there were no congenital anomalies, nor growth restriction. All children were normal physically and neurologically. We concluded that conservative breast surgery may be an alternative to mastectomy in the treatment of gestational breast cancer and is safe for the fetus. |
doi_str_mv | 10.1159/000087114 |
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Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, respectively. No local recurrences occurred with a median follow-up time of 87 months. Among the 10 patients treated with conservative surgery, 3 chose therapeutic abortion and 7 opted to continue their pregnancy. Concerning these 7 fetuses, there were no congenital anomalies, nor growth restriction. All children were normal physically and neurologically. We concluded that conservative breast surgery may be an alternative to mastectomy in the treatment of gestational breast cancer and is safe for the fetus.</description><identifier>ISSN: 1015-3837</identifier><identifier>EISSN: 1421-9964</identifier><identifier>DOI: 10.1159/000087114</identifier><identifier>PMID: 16113569</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Adult ; Biological and medical sciences ; Birth control ; Breast Neoplasms - pathology ; Breast Neoplasms - surgery ; Early Diagnosis ; Female ; Follow-Up Studies ; Gynecology. Andrology. Obstetrics ; Hormonal contraception ; Humans ; Mammary gland diseases ; Mastectomy, Segmental ; Medical sciences ; Neoplasm Staging ; Pilot Projects ; Pregnancy ; Pregnancy Complications, Neoplastic - surgery ; Pregnancy Outcome ; Pregnancy Trimester, Second ; Treatment Outcome ; Tumors</subject><ispartof>Fetal diagnosis and therapy, 2005-09, Vol.20 (5), p.442-444</ispartof><rights>2005 S. 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Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, respectively. No local recurrences occurred with a median follow-up time of 87 months. Among the 10 patients treated with conservative surgery, 3 chose therapeutic abortion and 7 opted to continue their pregnancy. Concerning these 7 fetuses, there were no congenital anomalies, nor growth restriction. All children were normal physically and neurologically. We concluded that conservative breast surgery may be an alternative to mastectomy in the treatment of gestational breast cancer and is safe for the fetus.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - surgery</subject><subject>Early Diagnosis</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hormonal contraception</subject><subject>Humans</subject><subject>Mammary gland diseases</subject><subject>Mastectomy, Segmental</subject><subject>Medical sciences</subject><subject>Neoplasm Staging</subject><subject>Pilot Projects</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Neoplastic - surgery</subject><subject>Pregnancy Outcome</subject><subject>Pregnancy Trimester, Second</subject><subject>Treatment Outcome</subject><subject>Tumors</subject><issn>1015-3837</issn><issn>1421-9964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpd0EtLw0AQB_BFFFurB8-CBEHBQ3Tfj6PGV6GgoJ7DdndTUtNEd5NCv71bU1pwL7MMP2aGPwCnCN4gxNQtjE8KhOgeGCKKUaoUp_vxDxFLiSRiAI5CmP8pwg_BAHGECONqCB7GdVFWrddtuXTJvXc6tEmma-N8Yjtf1rPkzbtZHTurRNc2yZo6OL_s_XvnZ86vjsFBoavgTjZ1BD6fHj-yl3Ty-jzO7iapIRy2qTUOYW4U5cbKeBu1RmqBFKOYESgJx05bKayyhmMMNZSFgZwJNxXSYsfJCFz1c79989O50OaLMhhXVbp2TRdyLqlSlIkIL_7BedP5Ot6WY4wJE5SQiK57ZHwTgndF_u3LhfarHMF8nWu-zTXa883Abrpwdic3QUZwuQE6GF0VPgZWhp0TkDAc7Qic9e5Lr6Pbgn7NLwMthlw</recordid><startdate>200509</startdate><enddate>200509</enddate><creator>Annane, Kadour</creator><creator>Bellocq, Jean-Pierre</creator><creator>Brettes, Jean-Philippe</creator><creator>Mathelin, Carole</creator><general>Karger</general><general>S. 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Andrology. Obstetrics</topic><topic>Hormonal contraception</topic><topic>Humans</topic><topic>Mammary gland diseases</topic><topic>Mastectomy, Segmental</topic><topic>Medical sciences</topic><topic>Neoplasm Staging</topic><topic>Pilot Projects</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Neoplastic - surgery</topic><topic>Pregnancy Outcome</topic><topic>Pregnancy Trimester, Second</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Annane, Kadour</creatorcontrib><creatorcontrib>Bellocq, Jean-Pierre</creatorcontrib><creatorcontrib>Brettes, Jean-Philippe</creatorcontrib><creatorcontrib>Mathelin, Carole</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Fetal diagnosis and therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Annane, Kadour</au><au>Bellocq, Jean-Pierre</au><au>Brettes, Jean-Philippe</au><au>Mathelin, Carole</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Infiltrative Breast Cancer during Pregnancy and Conservative Surgery</atitle><jtitle>Fetal diagnosis and therapy</jtitle><addtitle>Fetal Diagn Ther</addtitle><date>2005-09</date><risdate>2005</risdate><volume>20</volume><issue>5</issue><spage>442</spage><epage>444</epage><pages>442-444</pages><issn>1015-3837</issn><eissn>1421-9964</eissn><abstract>Mastectomy is considered as the standard therapy for gestational breast cancer. Since radiation therapy is harmful for the fetus, conservative surgery is rarely used during pregnancy. Among 16 patients with gestational breast cancer, 10 and 6 were treated with conservative surgery and mastectomy, respectively. No local recurrences occurred with a median follow-up time of 87 months. Among the 10 patients treated with conservative surgery, 3 chose therapeutic abortion and 7 opted to continue their pregnancy. Concerning these 7 fetuses, there were no congenital anomalies, nor growth restriction. All children were normal physically and neurologically. We concluded that conservative breast surgery may be an alternative to mastectomy in the treatment of gestational breast cancer and is safe for the fetus.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>16113569</pmid><doi>10.1159/000087114</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Biological and medical sciences Birth control Breast Neoplasms - pathology Breast Neoplasms - surgery Early Diagnosis Female Follow-Up Studies Gynecology. Andrology. Obstetrics Hormonal contraception Humans Mammary gland diseases Mastectomy, Segmental Medical sciences Neoplasm Staging Pilot Projects Pregnancy Pregnancy Complications, Neoplastic - surgery Pregnancy Outcome Pregnancy Trimester, Second Treatment Outcome Tumors |
title | Infiltrative Breast Cancer during Pregnancy and Conservative Surgery |
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