The PPARγ Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas

Peroxisome proliferator-activated receptor γ (PPARγ), a member of the nuclear hormone receptor superfamily initially shown to be a key regulator of fat cell differentiation, can inhibit cell growth and induce apoptosis in colon cell lines. There are heterozygous loss of function mutations in the gen...

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Veröffentlicht in:	Carcinogenesis (New York) 2005-03, Vol.26 (3), p.579-585
Hauptverfasser:	Gong, Zhihong, Xie, Dawen, Deng, Zonglin, Bostick, Roberd M., Muga, Stephanie J., Hurley, Thomas G., Hebert, James R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences BMI body mass index [weight (kg)/height (m)2] Carcinogenesis, carcinogens and anticarcinogens confidence interval Medical sciences non-steroidal anti-inflammatory drug NSAID odds ratio peroxisome proliferator-activated receptor γ PPARγ Tumors waist:hip ratio WHR
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