A New Fluoroquinolone Derivative Exhibits Inhibitory Activity against Human Immunodeficiency Virus Type 1 Replication

The inhibitory activity of several fluoroquinolone antibiotics against human immunodeficiency virus type 1 (HIV-1) replication was investigated. R-71762, (±) 9-fluoro-3-fluoromethyl-2,3-dihydro-10-[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid, protected MT...

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Veröffentlicht in:	Chemotherapy (Basel) 1999-01, Vol.45 (1), p.48-55
Hauptverfasser:	Kashiwase, Hiroto, Momota, Kenji, Ohmine, Toshinori, Komai, Tomoaki, Kimura, Tomio, Katsube, Tetsushi, Nishigaki, Takashi, Kimura, Satoshi, Shimada, Kaoru, Furukawa, Hidehiko
Format:	Artikel
Sprache:	eng
Schlagworte:	AIDS/HIV Anti-HIV Agents - pharmacology Anti-Infective Agents - pharmacology Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacteria - drug effects Biological and medical sciences Cytopathogenic Effect, Viral Experimental Chemotherapy HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus 1 Humans Levofloxacin Medical sciences Microbial Sensitivity Tests Ofloxacin - analogs & derivatives Ofloxacin - pharmacology Pharmacology. Drug treatments Tumor Cells, Cultured Virus Replication - drug effects
Online-Zugang:	Volltext
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