Prognostic Value of Change in Amniotic Fluid Color during Labor
Objective: Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color dur...
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| Veröffentlicht in: | Fetal diagnosis and therapy 2005-01, Vol.20 (1), p.5-9 |
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| creator | Locatelli, Anna Regalia, Anna Laura Patregnani, Cinzia Ratti, Marta Toso, Laura Ghidini, Alessandro |
| description | Objective: Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. Methods: AF characteristics on admission for labor at term (37–42 weeks) and their changes during labor were recorded in all singleton pregnancies during an 8-year period (1992–1999). Excluded were stillbirths on admission, congenital anomalies, and elective cesarean sections. The presence of meconium and its consistency (light or thick) were documented on admission by inspection with transcervical amnioscopy in women with intact membranes or in the vaginal pool in those with ruptured membranes. Changes in AF color or consistency during labor were recorded and correlated with the obstetric and neonatal outcome. Statistical analysis utilized χ 2 for trend, with p < 0.05 considered significant. Results: 19,090 women were admitted in labor at term during the study period and fulfilled the study inclusion criteria and had amniotic fluid evaluation available. The appearance of meconium or worsening in thickness of meconium during labor was associated with higher rates of Apgar scores |
| doi_str_mv | 10.1159/000081359 |
| format | Article |
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We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. Methods: AF characteristics on admission for labor at term (37–42 weeks) and their changes during labor were recorded in all singleton pregnancies during an 8-year period (1992–1999). Excluded were stillbirths on admission, congenital anomalies, and elective cesarean sections. The presence of meconium and its consistency (light or thick) were documented on admission by inspection with transcervical amnioscopy in women with intact membranes or in the vaginal pool in those with ruptured membranes. Changes in AF color or consistency during labor were recorded and correlated with the obstetric and neonatal outcome. Statistical analysis utilized χ 2 for trend, with p < 0.05 considered significant. Results: 19,090 women were admitted in labor at term during the study period and fulfilled the study inclusion criteria and had amniotic fluid evaluation available. The appearance of meconium or worsening in thickness of meconium during labor was associated with higher rates of Apgar scores <7 at 5 min (clear AF on admission and at delivery 0.6%; light or thick meconium on admission and no change at delivery 0.8%; clear AF on admission and light or thick meconium at delivery 3.2%, and light meconium on admission and thick meconium at delivery 2.5%; p < 0.001) and umbilical artery pH <7.10 (the respective rates in the four groups were 1.7, 1.8, 3.6, and 3.8%; p < 0.001). Conclusion: The appearance or thickening of meconium during labor has a greater predictive ability for depressed neonates than the presence of meconium on admission.</description><identifier>ISSN: 1015-3837</identifier><identifier>EISSN: 1421-9964</identifier><identifier>DOI: 10.1159/000081359</identifier><identifier>PMID: 15608450</identifier><language>eng</language><publisher>Basel, Switzerland: Karger</publisher><subject>Adult ; Amniotic Fluid - metabolism ; Apgar Score ; Biological and medical sciences ; Birth control ; Color ; Delivery. Postpartum. Lactation ; Female ; Gynecology. Andrology. Obstetrics ; Hormonal contraception ; Hospitalization ; Humans ; Labor, Obstetric - metabolism ; Meconium - chemistry ; Meconium - metabolism ; Medical sciences ; Predictive Value of Tests ; Pregnancy ; Pregnancy Outcome ; Prognosis ; Retrospective Studies</subject><ispartof>Fetal diagnosis and therapy, 2005-01, Vol.20 (1), p.5-9</ispartof><rights>2005 S. Karger AG, Basel</rights><rights>2005 INIST-CNRS</rights><rights>Copyright (c) 2005 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c387t-48fc9c0bc316cc0ab694f9cc6624ede0c2214288368b413a08dbbad34341da673</citedby><cites>FETCH-LOGICAL-c387t-48fc9c0bc316cc0ab694f9cc6624ede0c2214288368b413a08dbbad34341da673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2429,4024,27923,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16530035$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15608450$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Locatelli, Anna</creatorcontrib><creatorcontrib>Regalia, Anna Laura</creatorcontrib><creatorcontrib>Patregnani, Cinzia</creatorcontrib><creatorcontrib>Ratti, Marta</creatorcontrib><creatorcontrib>Toso, Laura</creatorcontrib><creatorcontrib>Ghidini, Alessandro</creatorcontrib><title>Prognostic Value of Change in Amniotic Fluid Color during Labor</title><title>Fetal diagnosis and therapy</title><addtitle>Fetal Diagn Ther</addtitle><description>Objective: Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. Methods: AF characteristics on admission for labor at term (37–42 weeks) and their changes during labor were recorded in all singleton pregnancies during an 8-year period (1992–1999). Excluded were stillbirths on admission, congenital anomalies, and elective cesarean sections. The presence of meconium and its consistency (light or thick) were documented on admission by inspection with transcervical amnioscopy in women with intact membranes or in the vaginal pool in those with ruptured membranes. Changes in AF color or consistency during labor were recorded and correlated with the obstetric and neonatal outcome. Statistical analysis utilized χ 2 for trend, with p < 0.05 considered significant. Results: 19,090 women were admitted in labor at term during the study period and fulfilled the study inclusion criteria and had amniotic fluid evaluation available. The appearance of meconium or worsening in thickness of meconium during labor was associated with higher rates of Apgar scores <7 at 5 min (clear AF on admission and at delivery 0.6%; light or thick meconium on admission and no change at delivery 0.8%; clear AF on admission and light or thick meconium at delivery 3.2%, and light meconium on admission and thick meconium at delivery 2.5%; p < 0.001) and umbilical artery pH <7.10 (the respective rates in the four groups were 1.7, 1.8, 3.6, and 3.8%; p < 0.001). Conclusion: The appearance or thickening of meconium during labor has a greater predictive ability for depressed neonates than the presence of meconium on admission.</description><subject>Adult</subject><subject>Amniotic Fluid - metabolism</subject><subject>Apgar Score</subject><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Color</subject><subject>Delivery. Postpartum. Lactation</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Hormonal contraception</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Labor, Obstetric - metabolism</subject><subject>Meconium - chemistry</subject><subject>Meconium - metabolism</subject><subject>Medical sciences</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome</subject><subject>Prognosis</subject><subject>Retrospective Studies</subject><issn>1015-3837</issn><issn>1421-9964</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0M9LwzAUB_AgipvTg2dBwkDBQzW_mqYnGdWpMNDD9FrSNK2dbTOT9eB_b-bqBmIuL_A-vPf4AnCK0TXGYXyD_BOYhvEeGGJGcBDHnO37P8JhQAWNBuDIucVaRZQfggEOORIsRENw-2JN2Rq3qhR8k3WnoSlg8i7bUsOqhZOmrcy6N627KoeJqY2FeWertoQzmRl7DA4KWTt90tcReJ3ez5PHYPb88JRMZoGiIloFTBQqVihTFHOlkMx4zIpYKc4J07lGihB_uBCUi4xhKpHIs0zmlFGGc8kjOgKXm7lLaz477VZpUzml61q22nQu9YREhDEPx3_gwnS29belhBAq_ELh0dUGKWucs7pIl7ZqpP1KMUrXkabbSL097wd2WaPznewz9OCiB9IpWRdWtqpyO8dDihANvTvbuA9pS2234HfN-N_u9G7-A9JlXtBv0MePmw</recordid><startdate>200501</startdate><enddate>200501</enddate><creator>Locatelli, Anna</creator><creator>Regalia, Anna Laura</creator><creator>Patregnani, Cinzia</creator><creator>Ratti, Marta</creator><creator>Toso, Laura</creator><creator>Ghidini, Alessandro</creator><general>Karger</general><general>S. Karger AG</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>200501</creationdate><title>Prognostic Value of Change in Amniotic Fluid Color during Labor</title><author>Locatelli, Anna ; Regalia, Anna Laura ; Patregnani, Cinzia ; Ratti, Marta ; Toso, Laura ; Ghidini, Alessandro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c387t-48fc9c0bc316cc0ab694f9cc6624ede0c2214288368b413a08dbbad34341da673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Amniotic Fluid - metabolism</topic><topic>Apgar Score</topic><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Color</topic><topic>Delivery. Postpartum. Lactation</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Hormonal contraception</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Labor, Obstetric - metabolism</topic><topic>Meconium - chemistry</topic><topic>Meconium - metabolism</topic><topic>Medical sciences</topic><topic>Predictive Value of Tests</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome</topic><topic>Prognosis</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Locatelli, Anna</creatorcontrib><creatorcontrib>Regalia, Anna Laura</creatorcontrib><creatorcontrib>Patregnani, Cinzia</creatorcontrib><creatorcontrib>Ratti, Marta</creatorcontrib><creatorcontrib>Toso, Laura</creatorcontrib><creatorcontrib>Ghidini, Alessandro</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Fetal diagnosis and therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Locatelli, Anna</au><au>Regalia, Anna Laura</au><au>Patregnani, Cinzia</au><au>Ratti, Marta</au><au>Toso, Laura</au><au>Ghidini, Alessandro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prognostic Value of Change in Amniotic Fluid Color during Labor</atitle><jtitle>Fetal diagnosis and therapy</jtitle><addtitle>Fetal Diagn Ther</addtitle><date>2005-01</date><risdate>2005</risdate><volume>20</volume><issue>1</issue><spage>5</spage><epage>9</epage><pages>5-9</pages><issn>1015-3837</issn><eissn>1421-9964</eissn><abstract>Objective: Evidence of meconium-stained amniotic fluid (AF) during labor suggests implementation of close monitoring of fetal well-being. We have investigated whether the presence of meconium in the AF on admission for labor is as important a predictor of neonatal outcome as a change in AF color during labor. Methods: AF characteristics on admission for labor at term (37–42 weeks) and their changes during labor were recorded in all singleton pregnancies during an 8-year period (1992–1999). Excluded were stillbirths on admission, congenital anomalies, and elective cesarean sections. The presence of meconium and its consistency (light or thick) were documented on admission by inspection with transcervical amnioscopy in women with intact membranes or in the vaginal pool in those with ruptured membranes. Changes in AF color or consistency during labor were recorded and correlated with the obstetric and neonatal outcome. Statistical analysis utilized χ 2 for trend, with p < 0.05 considered significant. Results: 19,090 women were admitted in labor at term during the study period and fulfilled the study inclusion criteria and had amniotic fluid evaluation available. The appearance of meconium or worsening in thickness of meconium during labor was associated with higher rates of Apgar scores <7 at 5 min (clear AF on admission and at delivery 0.6%; light or thick meconium on admission and no change at delivery 0.8%; clear AF on admission and light or thick meconium at delivery 3.2%, and light meconium on admission and thick meconium at delivery 2.5%; p < 0.001) and umbilical artery pH <7.10 (the respective rates in the four groups were 1.7, 1.8, 3.6, and 3.8%; p < 0.001). Conclusion: The appearance or thickening of meconium during labor has a greater predictive ability for depressed neonates than the presence of meconium on admission.</abstract><cop>Basel, Switzerland</cop><pub>Karger</pub><pmid>15608450</pmid><doi>10.1159/000081359</doi><tpages>5</tpages></addata></record> |
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| ispartof | Fetal diagnosis and therapy, 2005-01, Vol.20 (1), p.5-9 |
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| source | Karger Journal Archive Collection; MEDLINE; Karger Journals; Alma/SFX Local Collection |
| subjects | Adult Amniotic Fluid - metabolism Apgar Score Biological and medical sciences Birth control Color Delivery. Postpartum. Lactation Female Gynecology. Andrology. Obstetrics Hormonal contraception Hospitalization Humans Labor, Obstetric - metabolism Meconium - chemistry Meconium - metabolism Medical sciences Predictive Value of Tests Pregnancy Pregnancy Outcome Prognosis Retrospective Studies |
| title | Prognostic Value of Change in Amniotic Fluid Color during Labor |
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