The Caveolin genes: from cell biology to medicine

Caveolae are vesicular organelles (50-100-nm in diameter) that are particularly abundant in cells of the cardiovascular system, including endothelial cells, smooth muscle cells, macrophages, cardiac myocytes and fibroblasts. In these cell types, caveolae function both in protein trafficking and sign...

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Bibliographische Detailangaben
Veröffentlicht in:	Annals of medicine (Helsinki) 2004, Vol.36 (8), p.584-595
Hauptverfasser:	Williams, Terence M, Lisanti, Michael P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arteriosclerosis - genetics atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels cancer Cardiology. Vascular system Cardiomyopathies - genetics cardiomyopathy Caveolae - physiology Caveolin 1 Caveolins - genetics Disease Models, Animal Endocytosis - genetics Endocytosis - physiology Female Urogenital Diseases - genetics General aspects genetic disease Humans Lung Diseases - genetics Male Urogenital Diseases Medical sciences Mice Mice, Knockout Mitogen-Activated Protein Kinases - physiology mouse animal models Muscle, Smooth - cytology Muscular Dystrophies - genetics muscular dystrophy Neoplasms - genetics Signal Transduction - genetics src-Family Kinases - physiology vascular disease
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