Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes
To assess the value of immediate cytologic evaluation (ICE) in mediastinal endoscopic ultrasound-guided transesophageal fine needle aspiration (EUS-FNA). Fifty eight patients with mediastinal lymphadenopathy underwent transesophageal EUS-FNA. Cellularity, number of needle passes and number of slides...
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| Veröffentlicht in: | Acta cytologica 2004-09, Vol.48 (5), p.630-634 |
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| container_title | Acta cytologica |
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| creator | Emery, Shawn Clark Savides, Thomas J. Behling, Cynthia A. |
| description | To assess the value of immediate cytologic evaluation (ICE) in mediastinal endoscopic ultrasound-guided transesophageal fine needle aspiration (EUS-FNA).
Fifty eight patients with mediastinal lymphadenopathy underwent transesophageal EUS-FNA. Cellularity, number of needle passes and number of slides prepared were reviewed retrospectively.
Of moderate to highly cellular passes, 75% were diagnostic. ICE had a 100% positive predictive value and 97% negative predictive value. ICE allowed a diagnosis in all cases. Calculated diagnostic accuracy was 70% if the procedure ended after a single specimen of at least moderate cellularity or after completion of 4 needle passes.
Immediate cytologic evaluation of EUS-FNA specimens allowed a diagnosis in all cases and contributed to the utility of EUS-FNA as a diagnostic procedure for mediastinal adenopathy. |
| doi_str_mv | 10.1159/000326433 |
| format | Article |
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Fifty eight patients with mediastinal lymphadenopathy underwent transesophageal EUS-FNA. Cellularity, number of needle passes and number of slides prepared were reviewed retrospectively.
Of moderate to highly cellular passes, 75% were diagnostic. ICE had a 100% positive predictive value and 97% negative predictive value. ICE allowed a diagnosis in all cases. Calculated diagnostic accuracy was 70% if the procedure ended after a single specimen of at least moderate cellularity or after completion of 4 needle passes.
Immediate cytologic evaluation of EUS-FNA specimens allowed a diagnosis in all cases and contributed to the utility of EUS-FNA as a diagnostic procedure for mediastinal adenopathy.</description><identifier>ISSN: 0001-5547</identifier><identifier>EISSN: 1938-2650</identifier><identifier>DOI: 10.1159/000326433</identifier><identifier>PMID: 15471254</identifier><identifier>CODEN: ACYTAN</identifier><language>eng</language><publisher>Basel, Switzerland: Science Printers and Publishers</publisher><subject>Aged ; Biological and medical sciences ; Biopsy, Fine-Needle - methods ; Biopsy, Fine-Needle - standards ; Carcinoma - diagnosis ; Carcinoma - diagnostic imaging ; Carcinoma - secondary ; Diagnosis, Differential ; Endosonography - instrumentation ; Endosonography - methods ; Esophagus - diagnostic imaging ; Esophagus - surgery ; Female ; Fine Needle Aspiration ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; Lung Neoplasms - diagnosis ; Lung Neoplasms - diagnostic imaging ; Lung Neoplasms - secondary ; Lymph Nodes - diagnostic imaging ; Lymph Nodes - pathology ; Lymphatic Diseases - diagnostic imaging ; Lymphatic Diseases - pathology ; Male ; Mediastinum - diagnostic imaging ; Mediastinum - pathology ; Medical sciences ; Middle Aged ; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques ; Predictive Value of Tests ; Reproducibility of Results ; Retrospective Studies</subject><ispartof>Acta cytologica, 2004-09, Vol.48 (5), p.630-634</ispartof><rights>2011 S. Karger AG, Basel</rights><rights>2004 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-784bfda31946363a40db2b5b23abb25f3835e153e09859afbd93333447ce5bba3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,2427,27922,27923</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16117848$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15471254$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Emery, Shawn Clark</creatorcontrib><creatorcontrib>Savides, Thomas J.</creatorcontrib><creatorcontrib>Behling, Cynthia A.</creatorcontrib><title>Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes</title><title>Acta cytologica</title><addtitle>Acta Cytologica</addtitle><description>To assess the value of immediate cytologic evaluation (ICE) in mediastinal endoscopic ultrasound-guided transesophageal fine needle aspiration (EUS-FNA).
Fifty eight patients with mediastinal lymphadenopathy underwent transesophageal EUS-FNA. Cellularity, number of needle passes and number of slides prepared were reviewed retrospectively.
Of moderate to highly cellular passes, 75% were diagnostic. ICE had a 100% positive predictive value and 97% negative predictive value. ICE allowed a diagnosis in all cases. Calculated diagnostic accuracy was 70% if the procedure ended after a single specimen of at least moderate cellularity or after completion of 4 needle passes.
Immediate cytologic evaluation of EUS-FNA specimens allowed a diagnosis in all cases and contributed to the utility of EUS-FNA as a diagnostic procedure for mediastinal adenopathy.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Fine-Needle - methods</subject><subject>Biopsy, Fine-Needle - standards</subject><subject>Carcinoma - diagnosis</subject><subject>Carcinoma - diagnostic imaging</subject><subject>Carcinoma - secondary</subject><subject>Diagnosis, Differential</subject><subject>Endosonography - instrumentation</subject><subject>Endosonography - methods</subject><subject>Esophagus - diagnostic imaging</subject><subject>Esophagus - surgery</subject><subject>Female</subject><subject>Fine Needle Aspiration</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Lung Neoplasms - diagnosis</subject><subject>Lung Neoplasms - diagnostic imaging</subject><subject>Lung Neoplasms - secondary</subject><subject>Lymph Nodes - diagnostic imaging</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Diseases - diagnostic imaging</subject><subject>Lymphatic Diseases - pathology</subject><subject>Male</subject><subject>Mediastinum - diagnostic imaging</subject><subject>Mediastinum - pathology</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</subject><subject>Predictive Value of Tests</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><issn>0001-5547</issn><issn>1938-2650</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0M9r2zAUB3AxNtas22H3MQRjgx7cWdaP2McQ0q6QtZfmsJN5sp5bbbLlSvYgx_3nU4hJL9VF8Pjwld6XkI8sv2RMVt_zPOeFEpy_IgtW8TIrlMxfk0Was0xKsTwj72L8nRRXir8lZyzNWCHFgvzbjdbZcU99S2-6Do2FEenmL7gJRuv7w3zTGx8bP9iG7twYIPqpN9n1ZA0aeh-gjxj98AgPCI5e2R7pLaJxSFdxsOEU8_MQHkfbJ7Xdd8MjvfUG43vypgUX8cN8n5Pd1eZ-_SPb3l3frFfbrOEqH7NlKXRrgLNKKK44iNzoQktdcNC6kC0vuUQmOeZVKStotal4OkIsG5RaAz8n3465Q_BPE8ax7mxs0Dno0U-xVqqSouQswYsjbIKPMWBbD8F2EPY1y-tD3_Wp72Q_z6GTTuU9y7ngBL7OAGIDrk1tNTY-O8VY2qxM7svR_YHwgOEEVutfx6fqwbRJfXpRzb_5D-htnbg</recordid><startdate>20040901</startdate><enddate>20040901</enddate><creator>Emery, Shawn Clark</creator><creator>Savides, Thomas J.</creator><creator>Behling, Cynthia A.</creator><general>Science Printers and Publishers</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20040901</creationdate><title>Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes</title><author>Emery, Shawn Clark ; Savides, Thomas J. ; Behling, Cynthia A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-784bfda31946363a40db2b5b23abb25f3835e153e09859afbd93333447ce5bba3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Fine-Needle - methods</topic><topic>Biopsy, Fine-Needle - standards</topic><topic>Carcinoma - diagnosis</topic><topic>Carcinoma - diagnostic imaging</topic><topic>Carcinoma - secondary</topic><topic>Diagnosis, Differential</topic><topic>Endosonography - instrumentation</topic><topic>Endosonography - methods</topic><topic>Esophagus - diagnostic imaging</topic><topic>Esophagus - surgery</topic><topic>Female</topic><topic>Fine Needle Aspiration</topic><topic>Humans</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>Lung Neoplasms - diagnosis</topic><topic>Lung Neoplasms - diagnostic imaging</topic><topic>Lung Neoplasms - secondary</topic><topic>Lymph Nodes - diagnostic imaging</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Diseases - diagnostic imaging</topic><topic>Lymphatic Diseases - pathology</topic><topic>Male</topic><topic>Mediastinum - diagnostic imaging</topic><topic>Mediastinum - pathology</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques</topic><topic>Predictive Value of Tests</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Emery, Shawn Clark</creatorcontrib><creatorcontrib>Savides, Thomas J.</creatorcontrib><creatorcontrib>Behling, Cynthia A.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta cytologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Emery, Shawn Clark</au><au>Savides, Thomas J.</au><au>Behling, Cynthia A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes</atitle><jtitle>Acta cytologica</jtitle><addtitle>Acta Cytologica</addtitle><date>2004-09-01</date><risdate>2004</risdate><volume>48</volume><issue>5</issue><spage>630</spage><epage>634</epage><pages>630-634</pages><issn>0001-5547</issn><eissn>1938-2650</eissn><coden>ACYTAN</coden><abstract>To assess the value of immediate cytologic evaluation (ICE) in mediastinal endoscopic ultrasound-guided transesophageal fine needle aspiration (EUS-FNA).
Fifty eight patients with mediastinal lymphadenopathy underwent transesophageal EUS-FNA. Cellularity, number of needle passes and number of slides prepared were reviewed retrospectively.
Of moderate to highly cellular passes, 75% were diagnostic. ICE had a 100% positive predictive value and 97% negative predictive value. ICE allowed a diagnosis in all cases. Calculated diagnostic accuracy was 70% if the procedure ended after a single specimen of at least moderate cellularity or after completion of 4 needle passes.
Immediate cytologic evaluation of EUS-FNA specimens allowed a diagnosis in all cases and contributed to the utility of EUS-FNA as a diagnostic procedure for mediastinal adenopathy.</abstract><cop>Basel, Switzerland</cop><pub>Science Printers and Publishers</pub><pmid>15471254</pmid><doi>10.1159/000326433</doi><tpages>5</tpages></addata></record> |
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| ispartof | Acta cytologica, 2004-09, Vol.48 (5), p.630-634 |
| issn | 0001-5547 1938-2650 |
| language | eng |
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| source | MEDLINE; Karger Journals |
| subjects | Aged Biological and medical sciences Biopsy, Fine-Needle - methods Biopsy, Fine-Needle - standards Carcinoma - diagnosis Carcinoma - diagnostic imaging Carcinoma - secondary Diagnosis, Differential Endosonography - instrumentation Endosonography - methods Esophagus - diagnostic imaging Esophagus - surgery Female Fine Needle Aspiration Humans Investigative techniques, diagnostic techniques (general aspects) Lung Neoplasms - diagnosis Lung Neoplasms - diagnostic imaging Lung Neoplasms - secondary Lymph Nodes - diagnostic imaging Lymph Nodes - pathology Lymphatic Diseases - diagnostic imaging Lymphatic Diseases - pathology Male Mediastinum - diagnostic imaging Mediastinum - pathology Medical sciences Middle Aged Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Predictive Value of Tests Reproducibility of Results Retrospective Studies |
| title | Utility of Immediate Evaluation of Endoscopic Ultrasound-Guided Transesophageal Fine Needle Aspiration of Mediastinal Lymph Nodes |
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