Ala12Ala Genotype of the Peroxisome Proliferator-Activated Receptor γ2 Protects against Atherosclerosis

A mutation in the peroxisome proliferator-activated receptor γ2 (PPARγ2) gene with a cytosine to guanine substitution results in an exchange of proline (Pro) with alanine (Ala) in exon B (codon 12) of this gene. This polymorphism has been associated with high insulin sensitivity and low body weight,...

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Veröffentlicht in:The journal of clinical endocrinology and metabolism 2004-09, Vol.89 (9), p.4238-4242
Hauptverfasser: Temelkova-Kurktschiev, Theodora, Hanefeld, Markolf, Chinetti, Giulia, Zawadzki, Christophe, Haulon, Stephan, Kubaszek, Agata, Koehler, Carsta, Leonhardt, Wolfgang, Staels, Bart, Laakso, Markku
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Sprache:eng
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