Discovery, modeling, and human pharmacokinetics of N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)-thiophene -2-carboxamide (TBC3711), a second generation, ETA selective, and orally bioavailable endothelin antagonists

Bibliographische Detailangaben

Veröffentlicht in:	Journal of medicinal chemistry 2004, Vol.47 (8), p.1969-1986
Hauptverfasser:	WU, Chengde, DECKER, E. Radford, BROCK, Tommy A, DIXON, Richard A. F, BLOK, Natalie, HUONG BUI, YOU, Tony J, JUNMEI WANG, BOURGOYNE, Andree R, KNOWLES, Vippra, BERENS, Kurt L, HOLLAND, George W
Format:	Artikel
Sprache:	eng
Schlagworte:	Antihypertensive agents Biological and medical sciences Cardiovascular system Medical sciences Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Peptidergic system (neuropeptide, opioid peptide, opiates...). Adenosinergic and purinergic systems Pharmacology. Drug treatments
Online-Zugang:	Volltext
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