Protective Effects of Ethanolic Neem Leaf Extract on N-Methyl-N′-nitro-N-nitrosoguanidine-Induced Genotoxicity and Oxidative Stress in Mice

We evaluated the effects of pretreatment with ethanolic neem leaf extract on N-methyl-N′-nitro-N-nitrosoguanidine (MNNG)-induced genotoxicity and oxidative stress in male Swiss albino mice. The frequency of micronuclei (MN), concentrations of lipid peroxides and the status of the antioxidants, reduc...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Drug and chemical toxicology (New York, N.Y. 1978) N.Y. 1978), 2005-01, Vol.27 (1), p.15-26
Hauptverfasser:	Subapriya, R., Kumaraguruparan, R., Abraham, S. K., Nagini, S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Animals Antimutagenic Agents - pharmacology Antioxidants Azadirachta - chemistry Biological and medical sciences Bone Marrow Cells - cytology Bone Marrow Cells - drug effects Carcinogenesis, carcinogens and anticarcinogens Chemical agents Drug Therapy, Combination Glutathione Glutathione - metabolism Lipid Peroxidation - drug effects Male Medical sciences Methylnitronitrosoguanidine - toxicity Mice Micronuclei Micronucleus Tests MNNG Mutagens - toxicity Neem Oxidative stress Oxidative Stress - drug effects Plant Extracts - administration & dosage Plant Extracts - pharmacology Plant Leaves - chemistry Plants, Medicinal Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!