Kinetic Analysis of Reversible Inhibition of 16α-Hydroxyandrostenedione Aromatization in Human Placental Microsomes by Suicide Substrates of Androstenedione Aromatization

To gain insight into the catalytic function of aromatase and its substrate specificity, we studied reversible inhibition of 16α-hydroxyandrostenedione (16α-OHAD) aromatization in human placental microsomes by several suicide substrates of androstenedione (AD) aromatization, including 4-hydroxyAD (1)...

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Veröffentlicht in:	Biological & pharmaceutical bulletin 2003, Vol.26(6), pp.890-892
Hauptverfasser:	Numazawa, Mitsuteru, Mutsumi, Ayako, Tachibana, Mii, Yoshimura, Akiko
Format:	Artikel
Sprache:	eng
Schlagworte:	16α-hydroxyandrostenedione aromatization binding site Biological and medical sciences human placental aromatase Medical sciences reversible inhibition suicide substrate
Online-Zugang:	Volltext
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