Triterpene constituents from the leaves of Melicope indica

Phytochemical investigation of a petroleum ether extract of Melicope indica afforded two unusual pentacyclic triterpenes viz. neohop-13(18)-en-3α-ol (1) and fern-8(9)-en-3β-ol (2) and the ubiquitous steroids, stigmasterol and sitosterol. The structures of 1 and 2 were independently elucidated on the...

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Veröffentlicht in:Pharmazie 2003-07, Vol.58 (7), p.518-520
Hauptverfasser: Farruque, R., Chowdhury, R., Sohrab, M. H., Hasan, C. M., Rashid, M. A.
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Sprache:eng
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Zusammenfassung:Phytochemical investigation of a petroleum ether extract of Melicope indica afforded two unusual pentacyclic triterpenes viz. neohop-13(18)-en-3α-ol (1) and fern-8(9)-en-3β-ol (2) and the ubiquitous steroids, stigmasterol and sitosterol. The structures of 1 and 2 were independently elucidated on the basis of 2D NMR data and confirmed by comparison with those of related compounds. While compound 1 is a new natural product, this is the first report of occurrence of fern-8(9)-en-3β-ol (2) from the genus Melicope.
ISSN:0031-7144