OLFACTORY NEUROBLASTOMA AS A SECOND MALIGNANT NEOPLASM IN A PATIENT PREVIOUSLY TREATED FOR CHILDHOOD ACUTE LEUKEMIA

Various kinds of second malignant neoplasms after successful treatment for childhood acute leukemia have been reported. The authors describe an unusual case of an olfactory neuroblastoma in a patient previously treated for childhood acute leukemia including autologous bone marrow transplantation. Th...

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Veröffentlicht in:Pediatric hematology and oncology 2001, Vol.18 (7), p.459-463
Hauptverfasser: Kounami, Shinji, Douno, Sumitaka, Matsubara, Hiroshi, Takayama, Jun, Ohira, Mutsuro
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container_end_page 463
container_issue 7
container_start_page 459
container_title Pediatric hematology and oncology
container_volume 18
creator Kounami, Shinji
Douno, Sumitaka
Matsubara, Hiroshi
Takayama, Jun
Ohira, Mutsuro
description Various kinds of second malignant neoplasms after successful treatment for childhood acute leukemia have been reported. The authors describe an unusual case of an olfactory neuroblastoma in a patient previously treated for childhood acute leukemia including autologous bone marrow transplantation. The prophylactic cranial irradiation and the total body irradiation during autologous bone marrow transplantation may have induced the development of their patient's olfactory neuroblastoma. Although a second primary olfactory neuroblastoma is rare, it should be added to the list of second malignant neoplasmsin the sinonasal region.
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Myelofibrosis ; Medical sciences ; Neoplasms, Second Primary - etiology ; Neoplasms, Second Primary - pathology ; Neurology ; Olfactory Neuroblastoma ; Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy ; Second Malignant Neoplasm ; Transplantation, Autologous ; Tumors of the nervous system. 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The authors describe an unusual case of an olfactory neuroblastoma in a patient previously treated for childhood acute leukemia including autologous bone marrow transplantation. The prophylactic cranial irradiation and the total body irradiation during autologous bone marrow transplantation may have induced the development of their patient's olfactory neuroblastoma. 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Myelofibrosis</subject><subject>Medical sciences</subject><subject>Neoplasms, Second Primary - etiology</subject><subject>Neoplasms, Second Primary - pathology</subject><subject>Neurology</subject><subject>Olfactory Neuroblastoma</subject><subject>Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy</subject><subject>Second Malignant Neoplasm</subject><subject>Transplantation, Autologous</subject><subject>Tumors of the nervous system. 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Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Medical sciences</topic><topic>Neoplasms, Second Primary - etiology</topic><topic>Neoplasms, Second Primary - pathology</topic><topic>Neurology</topic><topic>Olfactory Neuroblastoma</topic><topic>Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy</topic><topic>Second Malignant Neoplasm</topic><topic>Transplantation, Autologous</topic><topic>Tumors of the nervous system. 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source MEDLINE; Taylor & Francis Medical Library - CRKN; Access via Taylor & Francis
subjects Acute Leukemia
Autologous Bone Marrow Transplantation
Biological and medical sciences
Bone Marrow Transplantation
Bone Neoplasms - diagnosis
Bone Neoplasms - secondary
Child
Esthesioneuroblastoma, Olfactory - etiology
Esthesioneuroblastoma, Olfactory - pathology
Fatal Outcome
Female
Hematologic and hematopoietic diseases
Humans
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Neoplasms, Second Primary - etiology
Neoplasms, Second Primary - pathology
Neurology
Olfactory Neuroblastoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma - therapy
Second Malignant Neoplasm
Transplantation, Autologous
Tumors of the nervous system. Phacomatoses
Whole-Body Irradiation - adverse effects
title OLFACTORY NEUROBLASTOMA AS A SECOND MALIGNANT NEOPLASM IN A PATIENT PREVIOUSLY TREATED FOR CHILDHOOD ACUTE LEUKEMIA
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