Potential Bile Acid Metabolites. 25. Synthesis and Chemical Properties of Stereoisomeric 3α,7α,16- and 3α,7α,15-Trihydroxy-5β-cholan-24-oic Acids

Epimeric 3α,7α,16- and 3α,7α,15-trihydroxy-5β-cholan-24-oic acids and some related compounds were synthesized from chenodeoxycholic acid (CDCA) and ursodeoxycholic acid (UDCA), respectively. The key reaction involved one-step remote oxyfunctionalization of unactivated methine carbons at C-17 of CDCA...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Chemical & pharmaceutical bulletin 2002, Vol.50(10), pp.1327-1334
Hauptverfasser:	Iida, Takashi, Hikosaka, Masahiro, Kakiyama, Genta, Shiraishi, Keisuke, Schteingart, Claudio D., Hagey, Lee R., Ton-Nu, Huong-Thu, Hofmann, Alan F., Mano, Nariyasu, Goto, Junichi, Nambara, Toshio
Format:	Artikel
Sprache:	eng
Schlagworte:	3α,7α,15-trihydroxy-5β-cholan-24-oic acid 3α,7α,16-trihydroxy-5β-cholan-24-oic acid Alicyclic compounds, terpenoids, prostaglandins, steroids Chemistry dimethyldioxirane Exact sciences and technology Organic chemistry Preparations and properties remote oxyfunctionalization Steroids ε-lactone
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!