PERINATAL COMPLICATIONS AS PREDICTORS OF INFANTILE AUTISM

This study investigated the relationship between reported perinatal complications and autism. The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the m...

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Veröffentlicht in:International journal of neuroscience 2002-09, Vol.112 (9), p.1085-1098
Hauptverfasser: WILKERSON, DIANA SUE, VOLPE, ALESSANDRA G., DEAN, RAYMOND S., TITUS, JEFFREY B.
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container_end_page 1098
container_issue 9
container_start_page 1085
container_title International journal of neuroscience
container_volume 112
creator WILKERSON, DIANA SUE
VOLPE, ALESSANDRA G.
DEAN, RAYMOND S.
TITUS, JEFFREY B.
description This study investigated the relationship between reported perinatal complications and autism. The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the mother. Previous research in this area has been limited, with no definitive conclusions. A discriminant analysis was performed to consider perinatal complications as predictors between the autistic and normal subjects. Using the MPS, 65% of the autistic cases were correctly grouped. The results further indicated significant differences on 3 of the 10 factors of the MPS, in particular, Gestational Age, Maternal Morphology, and Intrauterine Stress. When considered in an item by item fashion, 5 items were found to significantly predict group membership (prescriptions taken during pregnancy, length of labor, viral infection, abnormal presentation at delivery, and low birth weight). Finally, 3 maternal medical conditions were found to be highly significant and contribute to the separation between groups, including urinary infection, high temperatures, and depression.
doi_str_mv 10.1080/00207450290026076
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The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the mother. Previous research in this area has been limited, with no definitive conclusions. A discriminant analysis was performed to consider perinatal complications as predictors between the autistic and normal subjects. Using the MPS, 65% of the autistic cases were correctly grouped. The results further indicated significant differences on 3 of the 10 factors of the MPS, in particular, Gestational Age, Maternal Morphology, and Intrauterine Stress. When considered in an item by item fashion, 5 items were found to significantly predict group membership (prescriptions taken during pregnancy, length of labor, viral infection, abnormal presentation at delivery, and low birth weight). 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The biological mothers of 183 autistic children and 209 normals completed the Maternal Perinatal Scale (MPS), a maternal self-report that surveys complications of pregnancies and medical conditions of the mother. Previous research in this area has been limited, with no definitive conclusions. A discriminant analysis was performed to consider perinatal complications as predictors between the autistic and normal subjects. Using the MPS, 65% of the autistic cases were correctly grouped. The results further indicated significant differences on 3 of the 10 factors of the MPS, in particular, Gestational Age, Maternal Morphology, and Intrauterine Stress. When considered in an item by item fashion, 5 items were found to significantly predict group membership (prescriptions taken during pregnancy, length of labor, viral infection, abnormal presentation at delivery, and low birth weight). Finally, 3 maternal medical conditions were found to be highly significant and contribute to the separation between groups, including urinary infection, high temperatures, and depression.</description><subject>Adult</subject><subject>Autism</subject><subject>Autistic Disorder - epidemiology</subject><subject>Autistic Disorder - etiology</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Child clinical studies</subject><subject>Developmental disorders</subject><subject>Female</subject><subject>Humans</subject><subject>Infantile autism</subject><subject>Intelligence Tests</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Multivariate Analysis</subject><subject>Neuropsychological Tests</subject><subject>Perinatal Complications</subject><subject>Perinatal Predictors</subject><subject>Perinatology</subject><subject>Predictive Value of Tests</subject><subject>Pregnancy</subject><subject>Pregnancy Complications</subject><subject>Psychology. 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Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>WILKERSON, DIANA SUE</creatorcontrib><creatorcontrib>VOLPE, ALESSANDRA G.</creatorcontrib><creatorcontrib>DEAN, RAYMOND S.</creatorcontrib><creatorcontrib>TITUS, JEFFREY B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of neuroscience</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>WILKERSON, DIANA SUE</au><au>VOLPE, ALESSANDRA G.</au><au>DEAN, RAYMOND S.</au><au>TITUS, JEFFREY B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PERINATAL COMPLICATIONS AS PREDICTORS OF INFANTILE AUTISM</atitle><jtitle>International journal of neuroscience</jtitle><addtitle>Int J Neurosci</addtitle><date>2002-09-01</date><risdate>2002</risdate><volume>112</volume><issue>9</issue><spage>1085</spage><epage>1098</epage><pages>1085-1098</pages><issn>0020-7454</issn><eissn>1563-5279</eissn><eissn>1543-5245</eissn><coden>IJNUB7</coden><abstract>This study investigated the relationship between reported perinatal complications and autism. 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source Taylor & Francis; MEDLINE; Taylor & Francis Medical Library - CRKN
subjects Adult
Autism
Autistic Disorder - epidemiology
Autistic Disorder - etiology
Biological and medical sciences
Case-Control Studies
Chi-Square Distribution
Child
Child clinical studies
Developmental disorders
Female
Humans
Infantile autism
Intelligence Tests
Male
Medical sciences
Multivariate Analysis
Neuropsychological Tests
Perinatal Complications
Perinatal Predictors
Perinatology
Predictive Value of Tests
Pregnancy
Pregnancy Complications
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Retrospective Studies
Risk Factors
title PERINATAL COMPLICATIONS AS PREDICTORS OF INFANTILE AUTISM
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