Sarcoplasmic Reticulum Ca2/Calmodulin-Dependent Protein Kinase Is Altered in Heart Failure

ABSTRACTAlthough Ca/calmodulin-dependent protein kinase-II (CaMK) is known to phosphorylate different Ca cycling proteins in the cardiac sarcoplasmic reticulum (SR) and regulate its function, the status of CaMK in heart failure has not been investigated previously. In this study, we examined the hyp...

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Veröffentlicht in:Circulation research 2000-03, Vol.86 (5), p.596-605
Hauptverfasser: Netticadan, Thomas, Temsah, Rana M, Kawabata, Kenichi, Dhalla, Naranjan S
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Sprache:eng
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