Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes

Precise measurement of pHe in vivo may be of clinical value for both diagnosis and selection of therapy. pHe measurements made by the 31P probe 3‐aminopropylphosphonate (3‐APP) were compared with those made by the 19F probe, 3‐[N‐(4‐fluor‐2‐trifluoromethylphenyl)‐sulphamoyl]‐propionic acid (ZK‐15047...

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Veröffentlicht in:	NMR in biomedicine 1999-12, Vol.12 (8), p.495-504
Hauptverfasser:	Ojugo, Agatha S. E., McSheehy, Paul M. J., McIntyre, Dominick J. O., McCoy, Cheryl, Stubbs, Marion, Leach, Martin O., Judson, Ian R., Griffiths, John R.
Format:	Artikel
Sprache:	eng
Schlagworte:	19F- and 31P-MRS Biological and medical sciences extracellular pH Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) pH gradient solid tumours Tumors
Online-Zugang:	Volltext
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