Polyethylene Oxide Molecular Size Determines the Severity of Atypical Thrombotic Microangiopathy in a Guinea Pig Model of Acute Intravenous Exposure

Abstract In 2017, Opana ER was voluntarily removed from the U.S. market based on concerns that its risks outweighed its therapeutic benefits. The data that supported this conclusion were based on postmarketing evaluation that demonstrated increased intravenous abuse associated outbreaks of HIV, hepa...

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Veröffentlicht in:	Toxicological sciences 2020-09, Vol.177 (1), p.235-247
Hauptverfasser:	Baek, Jin Hyen, Shin, Hye Kyung H, Koo, Soo Min, Gao, Yamei, Qu, Haiou, Feng, Xin, Xu, Xiaoming, Pinto, Julia, Katneni, Upendra, Kimchi-Sarfaty, Chava, Buehler, Paul W
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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