P0420PARTIAL PHARMACOGENETIC PODOCYTE DEPLETION IN A HIGH-THROUGHPUT ZEBRAFISH MODEL RESEMBLES HUMAN FOCAL AND SEGMENTAL GLOMERULOSCLEROSIS

Abstract Background and Aims Although focal and segmental glomerulosclerosis (FSGS) has been in the scientific focus for many years, it is still a massive burden for patients with no causal therapeutic option. In FSGS, glomerular podocytes are injured, parietal epithelial cells (PECs) are activated...

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Veröffentlicht in:Nephrology, dialysis, transplantation dialysis, transplantation, 2020-06, Vol.35 (Supplement_3)
Hauptverfasser: Siegerist, Florian, Hansen, Kerrin Ursula Ingeborg, Daniel, Sophie, Schindler, Maximilian, Blumenthal, Antje, Zhou, Weibin, Endlich, Karlhans, Endlich, Nicole
Format: Artikel
Sprache:eng
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