Whole genome sequence of first Candida auris strain, isolated in Russia

Whole genome sequence of first Candida auris strain, isolated in Russia

Abstract Candida auris is an emergent yeast pathogen, easily transmissible between patients and with high percent of multidrug resistant strains. Here we present a draft genome sequence of the first known Russian strain of C. auris, isolated from a case of candidemia. The strain clustered within Sou...

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Veröffentlicht in:Medical mycology (Oxford) 2020-04, Vol.58 (3), p.414-416
Hauptverfasser: Pchelin, Ivan M, Azarov, Daniil V, Churina, Maria A, Ryabinin, Igor A, Vibornova, Irina V, Apalko, Svetlana V, Kruglov, Alexander N, Sarana, Andrey M, Taraskina, Anastasia E, Vasilyeva, Natalya V
Format: Artikel
Sprache:eng
Schlagworte:
Infectious Diseases
Life Sciences & Biomedicine
Mycology
Science & Technology
Veterinary Sciences
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Zusammenfassung:Abstract Candida auris is an emergent yeast pathogen, easily transmissible between patients and with high percent of multidrug resistant strains. Here we present a draft genome sequence of the first known Russian strain of C. auris, isolated from a case of candidemia. The strain clustered within South Asian C. auris clade and seemingly represented an independent event of dissemination from the original species range. Observed fluconazole resistance was probably due to F105L and K143R mutations in ERG11.
ISSN:1369-3786
1460-2709
DOI:10.1093/mmy/myz078