Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer’s disease

Abstract The transient receptor potential vanilloid 1 (TRPV1) protein is a pain receptor that elicits a hot sensation when an organism eats the capsaicin of red chili peppers. This calcium (Ca2+)-permeable cation channel is mostly expressed in the peripheral nervous system sensory neurons but also i...

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Veröffentlicht in:	Human molecular genetics 2020-01, Vol.29 (2), p.228-237
Hauptverfasser:	Kim, Juyong, Lee, Siyoung, Kim, Jaekyoon, Ham, Sangwoo, Park, Jung Han Yoon, Han, Seungbong, Jung, Yong-Keun, Shim, Insop, Han, Jung-Soo, Lee, Ki Won, Kim, Jiyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry & Molecular Biology Genetics & Heredity Life Sciences & Biomedicine Science & Technology
Online-Zugang:	Volltext
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