MO2-10-2Aged donor derived CAR-T exhibits enhanced effector functions but shorter persistence and less memory-like phenotypes

Abstract Background CD19 chimeric antigen receptor (CAR) T cell therapies have been successful in B cell malignancies. Recent reports about CD19 CAR T cell therapy in B-cell acute lymphoblastic leukemia suggest that the median event-free survival of children and young adult patients is longer than t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Annals of oncology 2019-10, Vol.30 (Supplement_6)
Hauptverfasser:	Kotani, Hiroshi, Li, Gongbo, Yao, Jiqiang, Mesa, Tania E, Chen, Jon, Yu, Bin, Boucher, Justin C, Yoder, Sean J, Zhou, Jing, Davila, Marco L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!