826PIdentification of a spectrum of germline mutations for hereditary diffuse gastric cancer in the Russian population by next-generation sequencing

Abstract Background Gastric cancer is the fifth most common malignancy in the world and the third leading cause of cancer death. Approximately 1–3% of gastric cancers are hereditary. Mutations of CDH1,the gene encoding E-cadherin, are the most common germline mutations detected in gastric cancer and...

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Veröffentlicht in:	Annals of oncology 2019-10, Vol.30 (Supplement_5)
Hauptverfasser:	Efimova, I U, Ignatova, E, Bykov, I, Kalinkin, A I, Tanas, A S, Alekseeva, E A, Strelnikov, V V, Alakunov, A, Kuznetsova, E, Nemtsova, M V
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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