522OMutation tracking in circulating tumour DNA (ctDNA) detects minimal residual disease (MRD) in patients with localized colorectal cancer (CRC) and identifies those at high risk of recurrence regardless of stage, lack of CDX2 expression and CMS subtype

Abstract Background Although staging provides prognostic information and guides therapeutic decisions, 30-50% of patients with localized CRC will relapse despite optimal primary treatment. CEA and imaging studies are insufficient to detect micrometastases at an early stage. The identification of pro...

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Veröffentlicht in:Annals of oncology 2019-10, Vol.30 (Supplement_5)
Hauptverfasser: Llavero, N Tarazona, Gimeno-Valiente, F, Gambardella, V, Huerta, M, Keranen, S Rosello, Bruixola, G, Fontana, E, Ciarpaglini, C Martinez, Zuñiga, S, Rentero, P, Fleitas, T, Papaccio, F, Moro, D, Pla, V, Nyamundanda, G, Castillo, J, Sadanadam, A, Espí, A, Roda, D, Cervantes, A
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Sprache:eng
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