174OPredictive and prognostic value of B-cell gene-expression signatures and B-cell receptor (BCR) repertoire in HER2+ breast cancer: A correlative analysis of the CALGB 40601 clinical trial (Alliance)

Abstract Background Although tumor-infiltrating lymphocytes density is associated with increased response and improved outcomes in HER2+ breast cancer, BCR clonal diversity repertoire could provide a more informative measure of an individual’s immune-mediated anti-tumor response. In this study, we f...

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Veröffentlicht in:	Annals of oncology 2019-10, Vol.30 (Supplement_5)
Hauptverfasser:	Fernandez-Martinez, A, Tanioka, M, Fan, C, Parker, J S, Hoadley, K A, Krop, I, Partridge, A, Carey, L, Perou, C M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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