57PThe expression of MMR, CD133 and the presence of p53 wt predict the response to cabazitaxel in malignant neural tumours cell lines

Abstract Background Cabazitaxel is used in the treatment of metastatic prostate cancer. It is not a substrate of P-glycoprotein, which is involved in cellular detoxification of chemotherapeutic agents and in the expulsion of drugs at blood-brain barrier. Our objectives are to test Cabazitaxel in vit...

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Veröffentlicht in:	Annals of oncology 2019-10, Vol.30 (Supplement_5)
Hauptverfasser:	Doello, K, Mesas, C, Perazzoli, G, García-Collado, C, Gándara, M J, García-Fumero, R, Fuel, M, Luque, R, Ortiz, R, Melguizo, C, Prados, J C
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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