Structure of the Protein Phosphatase 2A Holoenzyme

Protein Phosphatase 2A (PP2A) plays an essential role in many aspects of cellular physiology. The PP2A holoenzyme consists of a heterodimeric core enzyme, which comprises a scaffolding subunit and a catalytic subunit, and a variable regulatory subunit. Here we report the crystal structure of the het...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cell 2006-12, Vol.127 (6), p.1239-1251
Hauptverfasser:	Xu, Yanhui, Xing, Yongna, Chen, Yu, Chao, Yang, Lin, Zheng, Fan, Eugene, Yu, Jong W., Strack, Stefan, Jeffrey, Philip D., Shi, Yigong
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Catalytic Domain CRYSTAL STRUCTURE Crystallography, X-Ray FUNCTIONS Holoenzymes - chemistry Holoenzymes - metabolism Humans INTERFACES MATERIALS SCIENCE Methylation Models, Molecular Molecular Sequence Data Multiprotein Complexes - metabolism national synchrotron light source PHOSPHATASES Phosphoprotein Phosphatases - chemistry Phosphoprotein Phosphatases - metabolism PHYSIOLOGY Protein Conformation Protein Phosphatase 2 Protein Structure, Tertiary PROTEINS REGULATIONS Sequence Alignment Software SURFACES
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!