Actin-dependent propulsion of endosomes and lysosomes byrecruitment of n-wasp

We examined the spatial and temporal control of actin assembly in living Xenopus eggs. Within minutes of egg activation,dynamic actin-rich comet tails appeared on a subset of cytoplasmic vesicles that were enriched in protein kinase C (PKC), causing the vesicles to move through the cytoplasm. Actin...

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Veröffentlicht in:The Journal of cell biology 2000-02, Vol.148 (3)
Hauptverfasser: Taunton J, Rowning BA, Coughlin ML, Wu M, Moon RT, Mitchison TJ, Larabell CA
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Sprache:eng
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