Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis
In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudo...
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Veröffentlicht in: | Clinical nuclear medicine 1989-12, Vol.14 (12), p.877-880 |
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description | In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess. |
doi_str_mv | 10.1097/00003072-198912000-00003 |
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M ; DHEKNE, R. D ; MOORE, W. H</creator><creatorcontrib>DAVIDSON, R. M ; DHEKNE, R. D ; MOORE, W. H</creatorcontrib><description>In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/00003072-198912000-00003</identifier><identifier>PMID: 2605842</identifier><identifier>CODEN: CNMEDK</identifier><language>eng</language><publisher>Philadelphia, PA: Lippincott</publisher><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics ; Adult ; BETA DECAY RADIOISOTOPES ; BETA-MINUS DECAY RADIOISOTOPES ; Biological and medical sciences ; BIOLOGICAL MATERIALS ; BLOOD ; BLOOD CELLS ; BODY ; BODY FLUIDS ; Chemical and Drug Induced Liver Injury - diagnostic imaging ; COLLOIDS ; COUNTING TECHNIQUES ; DAYS LIVING RADIOISOTOPES ; DIAGNOSIS ; DIAGNOSTIC TECHNIQUES ; DIGESTIVE SYSTEM ; DIGESTIVE SYSTEM DISEASES ; DISEASES ; DISPERSIONS ; Drug toxicity and drugs side effects treatment ; ELECTRON CAPTURE RADIOISOTOPES ; Female ; GLANDS ; HEPATITIS ; HOURS LIVING RADIOISOTOPES ; Humans ; INDIUM 111 ; INDIUM ISOTOPES ; Indium Radioisotopes ; INTERMEDIATE MASS NUCLEI ; ISOMERIC NUCLEI ; ISOMERIC TRANSITION ISOTOPES ; ISOTOPES ; LEUKOCYTES ; LIVER ; Liver - diagnostic imaging ; MATERIALS ; Medical sciences ; MINUTES LIVING RADIOISOTOPES ; NUCLEI ; ODD-EVEN NUCLEI ; ORGANS ; Pharmacology. Drug treatments ; RADIOISOTOPE SCANNING ; RADIOISOTOPES ; RADIOLOGY AND NUCLEAR MEDICINE ; Radionuclide Imaging ; SCINTISCANNING ; TECHNETIUM 99 ; TECHNETIUM ISOTOPES ; Technetium Tc 99m Sulfur Colloid ; Toxicity: digestive system ; YEARS LIVING RADIOISOTOPES</subject><ispartof>Clinical nuclear medicine, 1989-12, Vol.14 (12), p.877-880</ispartof><rights>1991 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,778,782,883,27911,27912</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19525478$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2605842$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/7105512$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>DAVIDSON, R. M</creatorcontrib><creatorcontrib>DHEKNE, R. D</creatorcontrib><creatorcontrib>MOORE, W. H</creatorcontrib><title>Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis</title><title>Clinical nuclear medicine</title><addtitle>Clin Nucl Med</addtitle><description>In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess.</description><subject>550601 - Medicine- Unsealed Radionuclides in Diagnostics</subject><subject>Adult</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BETA-MINUS DECAY RADIOISOTOPES</subject><subject>Biological and medical sciences</subject><subject>BIOLOGICAL MATERIALS</subject><subject>BLOOD</subject><subject>BLOOD CELLS</subject><subject>BODY</subject><subject>BODY FLUIDS</subject><subject>Chemical and Drug Induced Liver Injury - diagnostic imaging</subject><subject>COLLOIDS</subject><subject>COUNTING TECHNIQUES</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DIAGNOSIS</subject><subject>DIAGNOSTIC TECHNIQUES</subject><subject>DIGESTIVE SYSTEM</subject><subject>DIGESTIVE SYSTEM DISEASES</subject><subject>DISEASES</subject><subject>DISPERSIONS</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>Female</subject><subject>GLANDS</subject><subject>HEPATITIS</subject><subject>HOURS LIVING RADIOISOTOPES</subject><subject>Humans</subject><subject>INDIUM 111</subject><subject>INDIUM ISOTOPES</subject><subject>Indium Radioisotopes</subject><subject>INTERMEDIATE MASS NUCLEI</subject><subject>ISOMERIC NUCLEI</subject><subject>ISOMERIC TRANSITION ISOTOPES</subject><subject>ISOTOPES</subject><subject>LEUKOCYTES</subject><subject>LIVER</subject><subject>Liver - diagnostic imaging</subject><subject>MATERIALS</subject><subject>Medical sciences</subject><subject>MINUTES LIVING RADIOISOTOPES</subject><subject>NUCLEI</subject><subject>ODD-EVEN NUCLEI</subject><subject>ORGANS</subject><subject>Pharmacology. Drug treatments</subject><subject>RADIOISOTOPE SCANNING</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radionuclide Imaging</subject><subject>SCINTISCANNING</subject><subject>TECHNETIUM 99</subject><subject>TECHNETIUM ISOTOPES</subject><subject>Technetium Tc 99m Sulfur Colloid</subject><subject>Toxicity: digestive system</subject><subject>YEARS LIVING RADIOISOTOPES</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j1tLAzEQhYMotVZ_ghAEH6OZXDbJoxYvhYIvio9Ldpqlke1u2WRB_73BFudlmHMOw_kIocDvgDtzz8tIbgQDZx2IcrE_6YTMQcuKcSHcKZlzWUnmTCXOyUVKX5xDBZWakZmouLZKzMnDqt_EaccAgH4-LmlC39PYU49TDjQP3xEphj6PsRuaqfMj3Ya9z0XtA45DiumSnLW-S-HquBfk4_npffnK1m8vq-XDmg1gbGZOBdFYia3lJgRpZRDIlXRegSgI0HAsKKG1ChqFbSN9JbRB5VG7oFolF-Tm8HdIOdYJYw64xaEvPXJtgGsNooSuD6H91OzCpt6PcefHn_rIW_zbo-8LadeOvseY_mPgtNDKWPkLLBljnw</recordid><startdate>198912</startdate><enddate>198912</enddate><creator>DAVIDSON, R. M</creator><creator>DHEKNE, R. D</creator><creator>MOORE, W. H</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>OTOTI</scope></search><sort><creationdate>198912</creationdate><title>Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis</title><author>DAVIDSON, R. M ; DHEKNE, R. D ; MOORE, W. H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-o178t-94e2b83cf807ee383e2c0439a4128911b0c989ef841b4cfb3a6257c4ac59e4f43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1989</creationdate><topic>550601 - Medicine- Unsealed Radionuclides in Diagnostics</topic><topic>Adult</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>Biological and medical sciences</topic><topic>BIOLOGICAL MATERIALS</topic><topic>BLOOD</topic><topic>BLOOD CELLS</topic><topic>BODY</topic><topic>BODY FLUIDS</topic><topic>Chemical and Drug Induced Liver Injury - diagnostic imaging</topic><topic>COLLOIDS</topic><topic>COUNTING TECHNIQUES</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DIAGNOSIS</topic><topic>DIAGNOSTIC TECHNIQUES</topic><topic>DIGESTIVE SYSTEM</topic><topic>DIGESTIVE SYSTEM DISEASES</topic><topic>DISEASES</topic><topic>DISPERSIONS</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>Female</topic><topic>GLANDS</topic><topic>HEPATITIS</topic><topic>HOURS LIVING RADIOISOTOPES</topic><topic>Humans</topic><topic>INDIUM 111</topic><topic>INDIUM ISOTOPES</topic><topic>Indium Radioisotopes</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>ISOMERIC NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>LEUKOCYTES</topic><topic>LIVER</topic><topic>Liver - diagnostic imaging</topic><topic>MATERIALS</topic><topic>Medical sciences</topic><topic>MINUTES LIVING RADIOISOTOPES</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANS</topic><topic>Pharmacology. Drug treatments</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>SCINTISCANNING</topic><topic>TECHNETIUM 99</topic><topic>TECHNETIUM ISOTOPES</topic><topic>Technetium Tc 99m Sulfur Colloid</topic><topic>Toxicity: digestive system</topic><topic>YEARS LIVING RADIOISOTOPES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DAVIDSON, R. M</creatorcontrib><creatorcontrib>DHEKNE, R. D</creatorcontrib><creatorcontrib>MOORE, W. H</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>OSTI.GOV</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DAVIDSON, R. M</au><au>DHEKNE, R. D</au><au>MOORE, W. H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>1989-12</date><risdate>1989</risdate><volume>14</volume><issue>12</issue><spage>877</spage><epage>880</epage><pages>877-880</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><coden>CNMEDK</coden><abstract>In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>2605842</pmid><doi>10.1097/00003072-198912000-00003</doi><tpages>4</tpages></addata></record> |
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subjects | 550601 - Medicine- Unsealed Radionuclides in Diagnostics Adult BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES Biological and medical sciences BIOLOGICAL MATERIALS BLOOD BLOOD CELLS BODY BODY FLUIDS Chemical and Drug Induced Liver Injury - diagnostic imaging COLLOIDS COUNTING TECHNIQUES DAYS LIVING RADIOISOTOPES DIAGNOSIS DIAGNOSTIC TECHNIQUES DIGESTIVE SYSTEM DIGESTIVE SYSTEM DISEASES DISEASES DISPERSIONS Drug toxicity and drugs side effects treatment ELECTRON CAPTURE RADIOISOTOPES Female GLANDS HEPATITIS HOURS LIVING RADIOISOTOPES Humans INDIUM 111 INDIUM ISOTOPES Indium Radioisotopes INTERMEDIATE MASS NUCLEI ISOMERIC NUCLEI ISOMERIC TRANSITION ISOTOPES ISOTOPES LEUKOCYTES LIVER Liver - diagnostic imaging MATERIALS Medical sciences MINUTES LIVING RADIOISOTOPES NUCLEI ODD-EVEN NUCLEI ORGANS Pharmacology. Drug treatments RADIOISOTOPE SCANNING RADIOISOTOPES RADIOLOGY AND NUCLEAR MEDICINE Radionuclide Imaging SCINTISCANNING TECHNETIUM 99 TECHNETIUM ISOTOPES Technetium Tc 99m Sulfur Colloid Toxicity: digestive system YEARS LIVING RADIOISOTOPES |
title | Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis |
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