Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis

In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudo...

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Veröffentlicht in:Clinical nuclear medicine 1989-12, Vol.14 (12), p.877-880
Hauptverfasser: DAVIDSON, R. M, DHEKNE, R. D, MOORE, W. H
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container_title Clinical nuclear medicine
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creator DAVIDSON, R. M
DHEKNE, R. D
MOORE, W. H
description In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess.
doi_str_mv 10.1097/00003072-198912000-00003
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M</creatorcontrib><creatorcontrib>DHEKNE, R. D</creatorcontrib><creatorcontrib>MOORE, W. H</creatorcontrib><title>Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis</title><title>Clinical nuclear medicine</title><addtitle>Clin Nucl Med</addtitle><description>In this case of prolonged fever and abnormal liver functions, dual tracer scintigraphy with In-111 WBCs and Tc-99m SC led to a biopsy-proven diagnosis of severe acute toxic hepatitis (hepatocellular necrosis). Correlation of the Tc-99m SC scan findings with those previously reported for "pseudotumors" of the liver is discussed. A "pseudonormal" scan pattern is described for the In-111 WBC scintigraphy. 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Drug treatments</topic><topic>RADIOISOTOPE SCANNING</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radionuclide Imaging</topic><topic>SCINTISCANNING</topic><topic>TECHNETIUM 99</topic><topic>TECHNETIUM ISOTOPES</topic><topic>Technetium Tc 99m Sulfur Colloid</topic><topic>Toxicity: digestive system</topic><topic>YEARS LIVING RADIOISOTOPES</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DAVIDSON, R. M</creatorcontrib><creatorcontrib>DHEKNE, R. D</creatorcontrib><creatorcontrib>MOORE, W. 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Discordance between In-111 WBC and Tc-99m SC scintigraphy in this clinical setting should raise the possibility of hepatic necrosis as a diagnostic alternative to hepatic abscess.</abstract><cop>Philadelphia, PA</cop><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>2605842</pmid><doi>10.1097/00003072-198912000-00003</doi><tpages>4</tpages></addata></record>
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identifier ISSN: 0363-9762
ispartof Clinical nuclear medicine, 1989-12, Vol.14 (12), p.877-880
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language eng
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source MEDLINE; Journals@Ovid Complete
subjects 550601 - Medicine- Unsealed Radionuclides in Diagnostics
Adult
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
Biological and medical sciences
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
Chemical and Drug Induced Liver Injury - diagnostic imaging
COLLOIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DIGESTIVE SYSTEM DISEASES
DISEASES
DISPERSIONS
Drug toxicity and drugs side effects treatment
ELECTRON CAPTURE RADIOISOTOPES
Female
GLANDS
HEPATITIS
HOURS LIVING RADIOISOTOPES
Humans
INDIUM 111
INDIUM ISOTOPES
Indium Radioisotopes
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LEUKOCYTES
LIVER
Liver - diagnostic imaging
MATERIALS
Medical sciences
MINUTES LIVING RADIOISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
Pharmacology. Drug treatments
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY AND NUCLEAR MEDICINE
Radionuclide Imaging
SCINTISCANNING
TECHNETIUM 99
TECHNETIUM ISOTOPES
Technetium Tc 99m Sulfur Colloid
Toxicity: digestive system
YEARS LIVING RADIOISOTOPES
title Indium-111 WBC scan in acute toxic centrilobular hepatic necrosis
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