Activation of the Protein-Tyrosine Kinase Associated with the Bombesin Receptor Complex in Small Cell Lung Carcinomas
It has been hypothesized that bombesin-like peptides produced by small cell lung carcinomas may sustain deregulated proliferation through an autocrine mechanism. We have shown that the neuropeptide bombesin leads to the activation of a protein-tyrosine kinase that phosphorylates a 115-kDa protein (p...
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Veröffentlicht in: | Proceedings of the National Academy of Sciences - PNAS 1988-04, Vol.85 (7), p.2166-2170 |
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