Excretion of Iodine-123-Hippuran, Technetium-99m-Red Blood Cells, and Technetium-99m-Macroaggregated Albumin into Breast Milk

The amount of radioactivity excreted in breast milk following three different nuclear medicine procedures on twelve nursing mothers has been measured. Some of this information has already been incorporated into the latest guidelines on suspension of feeding after maternal radiopharmaceutical adminis...

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Veröffentlicht in:The Journal of nuclear medicine (1978) 1990-06, Vol.31 (6), p.978-984
Hauptverfasser: Rose, Marjorie R, Prescott, Mary C, Herman, Kenneth J
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container_issue 6
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container_title The Journal of nuclear medicine (1978)
container_volume 31
creator Rose, Marjorie R
Prescott, Mary C
Herman, Kenneth J
description The amount of radioactivity excreted in breast milk following three different nuclear medicine procedures on twelve nursing mothers has been measured. Some of this information has already been incorporated into the latest guidelines on suspension of feeding after maternal radiopharmaceutical administration. The overall radiation dose that the patients' babies would have sustained had breast feeding not been interrupted has been estimated as an effective dose equivalent. A model has been developed to describe the relationship between clearance of activity from the milk, time between expressions, and the fraction of milk expressed. Some simple guidance is given on calculation of suitable interruption times for any individual mother from counts on her milk samples.
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Some of this information has already been incorporated into the latest guidelines on suspension of feeding after maternal radiopharmaceutical administration. The overall radiation dose that the patients' babies would have sustained had breast feeding not been interrupted has been estimated as an effective dose equivalent. A model has been developed to describe the relationship between clearance of activity from the milk, time between expressions, and the fraction of milk expressed. 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Some of this information has already been incorporated into the latest guidelines on suspension of feeding after maternal radiopharmaceutical administration. The overall radiation dose that the patients' babies would have sustained had breast feeding not been interrupted has been estimated as an effective dose equivalent. A model has been developed to describe the relationship between clearance of activity from the milk, time between expressions, and the fraction of milk expressed. 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POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>RADIOISOTOPES</subject><subject>RADIONUCLIDE KINETICS</subject><subject>RADIOPHARMACEUTICALS</subject><subject>Technetium - analysis</subject><subject>TECHNETIUM 99</subject><subject>TECHNETIUM ISOTOPES</subject><subject>Technetium Tc 99m Aggregated Albumin - metabolism</subject><subject>UPTAKE</subject><subject>VERTEBRATES</subject><subject>YEARS LIVING RADIOISOTOPES 560161 -- Radionuclide Effects, Kinetics, &amp; Toxicology-- Man</subject><issn>0161-5505</issn><issn>1535-5667</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0EtLxDAUBeAiio6PnyAEF64M5Nk0Sx3UERRBxnVI0nQm2iZjkqIu_O9WHBBc3c3H4dyzU80wpxzyuha71QzhGkPOET-oDnN-QQjVTdPsV_uEsoYwOqu-rj9scsXHAGIH7mLrg4OYULjwm82YdLgAS2fXYSLjAKUc4JNrwVUfYwvmru_zBdCh_W8etE1Rr1bJrXSZ_GVvxsEH4EOJ4Co5nQt48P3rcbXX6T67k-09qp5vrpfzBbx_vL2bX97DNalZgZ3VyCCBDa1FhzuGLWoMaRjqGJGiNS3WlnMpmDSMEUsdEYww6aQhBpOupUfV2W9uzMWrbH2Z-toYgrNF1QJRIeWEzn_RJsW30eWiBp_t9KMOLo5ZCSnktB-f4OkWjmZwrdokP-j0qbaj_gWt_Wr97pNTYbS90-kHv4SBYlUrKRr6DfadgC0</recordid><startdate>19900601</startdate><enddate>19900601</enddate><creator>Rose, Marjorie R</creator><creator>Prescott, Mary C</creator><creator>Herman, Kenneth J</creator><general>Soc Nuclear Med</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19900601</creationdate><title>Excretion of Iodine-123-Hippuran, Technetium-99m-Red Blood Cells, and Technetium-99m-Macroaggregated Albumin into Breast Milk</title><author>Rose, Marjorie R ; Prescott, Mary C ; Herman, Kenneth J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-h264t-fca0b071b367f1f41c08b2840f4297dbd1ac559749b442c3e274249e9b2b12fd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>ALBUMINS</topic><topic>AMINO ACIDS</topic><topic>ANIMALS</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>BIOLOGICAL MATERIALS</topic><topic>BLOOD</topic><topic>BLOOD CELLS</topic><topic>BODY FLUIDS</topic><topic>CARBOXYLIC ACIDS</topic><topic>DRUGS</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>ERYTHROCYTES</topic><topic>Female</topic><topic>FOOD</topic><topic>HIPPURIC ACID</topic><topic>HOURS LIVING RADIOISOTOPES</topic><topic>Humans</topic><topic>INTERMEDIATE MASS NUCLEI</topic><topic>IODINE 123</topic><topic>IODINE ISOTOPES</topic><topic>Iodine Radioisotopes - analysis</topic><topic>Iodohippuric Acid - metabolism</topic><topic>ISOMERIC NUCLEI</topic><topic>ISOMERIC TRANSITION ISOTOPES</topic><topic>ISOTOPES</topic><topic>LABELLED COMPOUNDS</topic><topic>LACTATION</topic><topic>Lactation - metabolism</topic><topic>MAMMALS</topic><topic>MAN</topic><topic>MATERIALS</topic><topic>MILK</topic><topic>Milk, Human - analysis</topic><topic>NUCLEI</topic><topic>ODD-EVEN NUCLEI</topic><topic>ORGANIC ACIDS</topic><topic>ORGANIC COMPOUNDS</topic><topic>PRIMATES</topic><topic>PROTEINS</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. 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Some of this information has already been incorporated into the latest guidelines on suspension of feeding after maternal radiopharmaceutical administration. The overall radiation dose that the patients' babies would have sustained had breast feeding not been interrupted has been estimated as an effective dose equivalent. A model has been developed to describe the relationship between clearance of activity from the milk, time between expressions, and the fraction of milk expressed. Some simple guidance is given on calculation of suitable interruption times for any individual mother from counts on her milk samples.</abstract><cop>United States</cop><pub>Soc Nuclear Med</pub><pmid>2348243</pmid><tpages>7</tpages></addata></record>
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ispartof The Journal of nuclear medicine (1978), 1990-06, Vol.31 (6), p.978-984
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals
subjects ALBUMINS
AMINO ACIDS
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACIDS
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
ERYTHROCYTES
Female
FOOD
HIPPURIC ACID
HOURS LIVING RADIOISOTOPES
Humans
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
Iodine Radioisotopes - analysis
Iodohippuric Acid - metabolism
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
LACTATION
Lactation - metabolism
MAMMALS
MAN
MATERIALS
MILK
Milk, Human - analysis
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
PRIMATES
PROTEINS
RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT
RADIOISOTOPES
RADIONUCLIDE KINETICS
RADIOPHARMACEUTICALS
Technetium - analysis
TECHNETIUM 99
TECHNETIUM ISOTOPES
Technetium Tc 99m Aggregated Albumin - metabolism
UPTAKE
VERTEBRATES
YEARS LIVING RADIOISOTOPES 560161 -- Radionuclide Effects, Kinetics, & Toxicology-- Man
title Excretion of Iodine-123-Hippuran, Technetium-99m-Red Blood Cells, and Technetium-99m-Macroaggregated Albumin into Breast Milk
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