Imaging of the heart using metaiodobenzylguanidine

Catecholamines have profound influences on cardiac function. Mechanisms relating abnormalities in sympathetic innervation to myocardial dysfunction are poorly understood, however. Recent studies have demonstrated the feasibility of noninvasively imaging the sympathetic nerves of the heart using radi...

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Veröffentlicht in:Journal of thoracic imaging 1990-07, Vol.5 (3), p.31-36
Hauptverfasser: Dae, Michael W, Botvinick, Elias H
Format: Artikel
Sprache:eng
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Zusammenfassung:Catecholamines have profound influences on cardiac function. Mechanisms relating abnormalities in sympathetic innervation to myocardial dysfunction are poorly understood, however. Recent studies have demonstrated the feasibility of noninvasively imaging the sympathetic nerves of the heart using radiolabeled MIBG. This article examines some of the experimental evidence to support the neuronal localization of MIBG. In addition, the early clinical experience is reviewed.
ISSN:0883-5993
1536-0237
DOI:10.1097/00005382-199007000-00007