California's proposition 65: Extrapolating animal toxicity to humans
In 1986, the voters of California passed a law regarding the concept of extrapolating animal toxicity data to humans. The California Safe Drinking Water and Toxic Enforcement Act of 1986, known as Proposition 65, does five things: 1 It creates a list of chemicals (including a number of agricultural...
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| Veröffentlicht in: | American journal of industrial medicine 1990, Vol.18 (4), p.491-494 |
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| creator | Kilgore, Wendell W. |
| description | In 1986, the voters of California passed a law regarding the concept of extrapolating animal toxicity data to humans. The California Safe Drinking Water and Toxic Enforcement Act of 1986, known as Proposition 65, does five things:
1
It creates a list of chemicals (including a number of agricultural chemicals) known to cause cancer or reproductive toxicity;
2
It limits discharges of listed chemicals to drinking water sources;
3
It requires prior warning before exposure to listed chemicals by anyone in the course of doing business;
4
It creates a list of chemicals requiring testing for carcinogenicity or reproductive toxicity; and
5
It requires the Governor to consult with qualified experts (a 12‐member “Scientific Advisory Panel” was appointed) as necessary to carry out his duties.
This paper discusses the details and implications of this proposition. Areas of responsibility have been assigned. The definition of significant risk is being addressed. |
| doi_str_mv | 10.1002/ajim.4700180422 |
| format | Article |
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1
It creates a list of chemicals (including a number of agricultural chemicals) known to cause cancer or reproductive toxicity;
2
It limits discharges of listed chemicals to drinking water sources;
3
It requires prior warning before exposure to listed chemicals by anyone in the course of doing business;
4
It creates a list of chemicals requiring testing for carcinogenicity or reproductive toxicity; and
5
It requires the Governor to consult with qualified experts (a 12‐member “Scientific Advisory Panel” was appointed) as necessary to carry out his duties.
This paper discusses the details and implications of this proposition. Areas of responsibility have been assigned. The definition of significant risk is being addressed.</description><identifier>ISSN: 0271-3586</identifier><identifier>EISSN: 1097-0274</identifier><identifier>DOI: 10.1002/ajim.4700180422</identifier><identifier>PMID: 2248253</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject><![CDATA[290300 - Energy Planning & Policy- Environment, Health, & Safety ; 540320 - Environment, Aquatic- Chemicals Monitoring & Transport- (1990-) ; 560300 - Chemicals Metabolism & Toxicology ; Abnormalities, Drug-Induced ; Animals ; BIOLOGICAL MODELS ; CALIFORNIA ; carcinogenicity ; Carcinogens, Environmental - analysis ; CONTAMINATION ; discharges of listed chemicals ; DRINKING WATER ; ENERGY PLANNING, POLICY AND ECONOMY ; ENVIRONMENTAL EXPOSURE ; Environmental Monitoring - legislation & jurisprudence ; Environmental Pollution - legislation & jurisprudence ; Environmental Pollution - prevention & control ; ENVIRONMENTAL SCIENCES ; FEDERAL REGION IX ; Humans ; HYDROGEN COMPOUNDS ; NORTH AMERICA ; OXYGEN COMPOUNDS ; POLLUTION ; Public Policy ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT ; reproductive toxicity ; Risk Factors ; TOXICITY ; USA ; WATER ; WATER POLLUTION ; Water Pollution, Chemical - legislation & jurisprudence ; Water Pollution, Chemical - prevention & control ; XENOBIOTICS]]></subject><ispartof>American journal of industrial medicine, 1990, Vol.18 (4), p.491-494</ispartof><rights>Copyright © 1990 Wiley Periodicals, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3552-32dc768c512a17ba88799ae4bb4819ccb19315e9b50d1d30f50a01f28eb214443</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fajim.4700180422$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fajim.4700180422$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,309,310,314,776,780,785,786,881,1411,4010,23909,23910,25118,27900,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2248253$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/6318496$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Kilgore, Wendell W.</creatorcontrib><title>California's proposition 65: Extrapolating animal toxicity to humans</title><title>American journal of industrial medicine</title><addtitle>Am. J. Ind. Med</addtitle><description>In 1986, the voters of California passed a law regarding the concept of extrapolating animal toxicity data to humans. The California Safe Drinking Water and Toxic Enforcement Act of 1986, known as Proposition 65, does five things:
1
It creates a list of chemicals (including a number of agricultural chemicals) known to cause cancer or reproductive toxicity;
2
It limits discharges of listed chemicals to drinking water sources;
3
It requires prior warning before exposure to listed chemicals by anyone in the course of doing business;
4
It creates a list of chemicals requiring testing for carcinogenicity or reproductive toxicity; and
5
It requires the Governor to consult with qualified experts (a 12‐member “Scientific Advisory Panel” was appointed) as necessary to carry out his duties.
This paper discusses the details and implications of this proposition. Areas of responsibility have been assigned. The definition of significant risk is being addressed.</description><subject>290300 - Energy Planning & Policy- Environment, Health, & Safety</subject><subject>540320 - Environment, Aquatic- Chemicals Monitoring & Transport- (1990-)</subject><subject>560300 - Chemicals Metabolism & Toxicology</subject><subject>Abnormalities, Drug-Induced</subject><subject>Animals</subject><subject>BIOLOGICAL MODELS</subject><subject>CALIFORNIA</subject><subject>carcinogenicity</subject><subject>Carcinogens, Environmental - analysis</subject><subject>CONTAMINATION</subject><subject>discharges of listed chemicals</subject><subject>DRINKING WATER</subject><subject>ENERGY PLANNING, POLICY AND ECONOMY</subject><subject>ENVIRONMENTAL EXPOSURE</subject><subject>Environmental Monitoring - legislation & jurisprudence</subject><subject>Environmental Pollution - legislation & jurisprudence</subject><subject>Environmental Pollution - prevention & control</subject><subject>ENVIRONMENTAL SCIENCES</subject><subject>FEDERAL REGION IX</subject><subject>Humans</subject><subject>HYDROGEN COMPOUNDS</subject><subject>NORTH AMERICA</subject><subject>OXYGEN COMPOUNDS</subject><subject>POLLUTION</subject><subject>Public Policy</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</subject><subject>reproductive toxicity</subject><subject>Risk Factors</subject><subject>TOXICITY</subject><subject>USA</subject><subject>WATER</subject><subject>WATER POLLUTION</subject><subject>Water Pollution, Chemical - legislation & jurisprudence</subject><subject>Water Pollution, Chemical - prevention & control</subject><subject>XENOBIOTICS</subject><issn>0271-3586</issn><issn>1097-0274</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1990</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM9P2zAUx61pU-k6zpyQoh3YKcXPPxJnnKq060AwODBxtBzXAUMSl9jV2v9-rlIx7cTpPel9vl-97xehE8BTwJicq2fbTlmOMQjMCPmAxoCLPMUkZx_ROA5IKRfZEfrs_XOkgGVshEaEMEE4HaN5qRpbu76z6ptP1r1bO2-DdV2S8e_JYht6tXaNCrZ7TFRnW9UkwW2ttmEXl-Rp06rOf0GfatV4c3yYE_T7x-K-_Jle3y4vy9l1qinnJKVkpfNMaA5EQV4pIfKiUIZVFRNQaF1BQYGbouJ4BSuKa44VhpoIUxFgjNEJ-jr4Oh-s9PEJo5-06zqjg8woCFZkEToboBjmdWN8kK312jSN6ozbeAlccCyAR_B8AHXvvO9NLdd9DNjvJGC5L1fuy5X_yo2K04P1pmrN6o0_tBnvF8P9j23M7j07Obu6vPnPPR3U1gezfVOr_kVmOc25fPi1lKSc35RzcSdL-heYtpQ0</recordid><startdate>1990</startdate><enddate>1990</enddate><creator>Kilgore, Wendell W.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TV</scope><scope>7U7</scope><scope>C1K</scope><scope>OTOTI</scope></search><sort><creationdate>1990</creationdate><title>California's proposition 65: Extrapolating animal toxicity to humans</title><author>Kilgore, Wendell W.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3552-32dc768c512a17ba88799ae4bb4819ccb19315e9b50d1d30f50a01f28eb214443</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1990</creationdate><topic>290300 - Energy Planning & Policy- Environment, Health, & Safety</topic><topic>540320 - Environment, Aquatic- Chemicals Monitoring & Transport- (1990-)</topic><topic>560300 - Chemicals Metabolism & Toxicology</topic><topic>Abnormalities, Drug-Induced</topic><topic>Animals</topic><topic>BIOLOGICAL MODELS</topic><topic>CALIFORNIA</topic><topic>carcinogenicity</topic><topic>Carcinogens, Environmental - analysis</topic><topic>CONTAMINATION</topic><topic>discharges of listed chemicals</topic><topic>DRINKING WATER</topic><topic>ENERGY PLANNING, POLICY AND ECONOMY</topic><topic>ENVIRONMENTAL EXPOSURE</topic><topic>Environmental Monitoring - legislation & jurisprudence</topic><topic>Environmental Pollution - legislation & jurisprudence</topic><topic>Environmental Pollution - prevention & control</topic><topic>ENVIRONMENTAL SCIENCES</topic><topic>FEDERAL REGION IX</topic><topic>Humans</topic><topic>HYDROGEN COMPOUNDS</topic><topic>NORTH AMERICA</topic><topic>OXYGEN COMPOUNDS</topic><topic>POLLUTION</topic><topic>Public Policy</topic><topic>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT</topic><topic>reproductive toxicity</topic><topic>Risk Factors</topic><topic>TOXICITY</topic><topic>USA</topic><topic>WATER</topic><topic>WATER POLLUTION</topic><topic>Water Pollution, Chemical - legislation & jurisprudence</topic><topic>Water Pollution, Chemical - prevention & control</topic><topic>XENOBIOTICS</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kilgore, Wendell W.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pollution Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>OSTI.GOV</collection><jtitle>American journal of industrial medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kilgore, Wendell W.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>California's proposition 65: Extrapolating animal toxicity to humans</atitle><jtitle>American journal of industrial medicine</jtitle><addtitle>Am. J. Ind. Med</addtitle><date>1990</date><risdate>1990</risdate><volume>18</volume><issue>4</issue><spage>491</spage><epage>494</epage><pages>491-494</pages><issn>0271-3586</issn><eissn>1097-0274</eissn><abstract>In 1986, the voters of California passed a law regarding the concept of extrapolating animal toxicity data to humans. The California Safe Drinking Water and Toxic Enforcement Act of 1986, known as Proposition 65, does five things:
1
It creates a list of chemicals (including a number of agricultural chemicals) known to cause cancer or reproductive toxicity;
2
It limits discharges of listed chemicals to drinking water sources;
3
It requires prior warning before exposure to listed chemicals by anyone in the course of doing business;
4
It creates a list of chemicals requiring testing for carcinogenicity or reproductive toxicity; and
5
It requires the Governor to consult with qualified experts (a 12‐member “Scientific Advisory Panel” was appointed) as necessary to carry out his duties.
This paper discusses the details and implications of this proposition. Areas of responsibility have been assigned. The definition of significant risk is being addressed.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2248253</pmid><doi>10.1002/ajim.4700180422</doi><tpages>4</tpages></addata></record> |
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| ispartof | American journal of industrial medicine, 1990, Vol.18 (4), p.491-494 |
| issn | 0271-3586 1097-0274 |
| language | eng |
| recordid | cdi_osti_scitechconnect_6318496 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | 290300 - Energy Planning & Policy- Environment, Health, & Safety 540320 - Environment, Aquatic- Chemicals Monitoring & Transport- (1990-) 560300 - Chemicals Metabolism & Toxicology Abnormalities, Drug-Induced Animals BIOLOGICAL MODELS CALIFORNIA carcinogenicity Carcinogens, Environmental - analysis CONTAMINATION discharges of listed chemicals DRINKING WATER ENERGY PLANNING, POLICY AND ECONOMY ENVIRONMENTAL EXPOSURE Environmental Monitoring - legislation & jurisprudence Environmental Pollution - legislation & jurisprudence Environmental Pollution - prevention & control ENVIRONMENTAL SCIENCES FEDERAL REGION IX Humans HYDROGEN COMPOUNDS NORTH AMERICA OXYGEN COMPOUNDS POLLUTION Public Policy RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT reproductive toxicity Risk Factors TOXICITY USA WATER WATER POLLUTION Water Pollution, Chemical - legislation & jurisprudence Water Pollution, Chemical - prevention & control XENOBIOTICS |
| title | California's proposition 65: Extrapolating animal toxicity to humans |
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