Biological monitoring of a worker acutely exposed to MBOCA

A 30 year‐old male polyurethane worker was exposed to an accidental spill of 4,4′‐methylene‐bis‐2‐chloroaniline (MBOCA) at a plant producing MBOCA‐cured plastic products. Exposure to MBOCA is significant in that this compound is a known animal carcinogen and a suspected human carcinogen. The employe...

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Veröffentlicht in:	American journal of industrial medicine 1990, Vol.18 (5), p.577-589
Hauptverfasser:	Osorio, Ana Maria, Clapp, David, Ward, Elizabeth, Wilson, H. Kerr, Cocker, John
Format:	Artikel
Sprache:	eng
Schlagworte:	4-4′-methylene-bis-2-chloroaniline 560300 - Chemicals Metabolism & Toxicology Accidents, Occupational ACUTE EXPOSURE Adult AMINES ANILINE AROMATICS BIOLOGICAL HALF-LIFE biological monitoring CARCINOGENESIS CAS # 101-14-4 Chemical Industry CHEMICAL SPILLS Child Chromatography, High Pressure Liquid dermal absorption Environmental Exposure Half-Life Humans INDUSTRY Kidney Function Tests kinetic analysis Liver Function Tests MBOCA METABOLISM Methylenebis(chloroaniline) - adverse effects Methylenebis(chloroaniline) - analysis Methylenebis(chloroaniline) - pharmacokinetics Monitoring, Physiologic OCCUPATIONAL EXPOSURE ORGANIC COMPOUNDS PATHOGENESIS PERSONNEL PLASTICS INDUSTRY polyurethane casting RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RECOMMENDATIONS urinary excretion
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