Interstitial Ir-192 implants of the oral cavity: The planning and construction of volume implants
The success of radioactive implant therapy for head and neck carcinomas depends critically on careful planning and execution of the implant procedure. In this paper we discuss our experience with oral tongue and floor of mouth implants, and some innovations introduced to facilitate these procedures....
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| Veröffentlicht in: | International journal of radiation oncology, biology, physics biology, physics, 1991-05, Vol.20 (5), p.1079-1085 |
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| container_title | International journal of radiation oncology, biology, physics |
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| creator | Schmidt-Ullrich, R. Zwicker, R.D. Wu, A. Kelly, Kathleen |
| description | The success of radioactive implant therapy for head and neck carcinomas depends critically on careful planning and execution of the implant procedure. In this paper we discuss our experience with oral tongue and floor of mouth implants, and some innovations introduced to facilitate these procedures. Implants were carried out using standard angiocatheters modified with magnetic caps at the open end and terminated with Teflon spacers and lead shot at the closed end. The importance of accurate source placement and careful determination of the target dose rate is discussed with numerical examples. Differential hot-loading of sources is clearly indicated in cases of extension of the lesion to the dorsal or lateral tongue surface. For dorsal surface extension the use of Teflon spacers at the closed ends of the catheters helps to ensure adequate coverage of the target volume with the higher dose region enclosing the demonstrable tumor. All 10 patients implanted with this technique are controlled without recurrence at a median follow-up of 38 months. The two complications observed appeared to be associated with excessive hot-loading of edge plane sources. |
| doi_str_mv | 10.1016/0360-3016(91)90208-L |
| format | Article |
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In this paper we discuss our experience with oral tongue and floor of mouth implants, and some innovations introduced to facilitate these procedures. Implants were carried out using standard angiocatheters modified with magnetic caps at the open end and terminated with Teflon spacers and lead shot at the closed end. The importance of accurate source placement and careful determination of the target dose rate is discussed with numerical examples. Differential hot-loading of sources is clearly indicated in cases of extension of the lesion to the dorsal or lateral tongue surface. For dorsal surface extension the use of Teflon spacers at the closed ends of the catheters helps to ensure adequate coverage of the target volume with the higher dose region enclosing the demonstrable tumor. All 10 patients implanted with this technique are controlled without recurrence at a median follow-up of 38 months. The two complications observed appeared to be associated with excessive hot-loading of edge plane sources.</description><subject>550603 - Medicine- External Radiation in Therapy- (1980-)</subject><subject>BETA DECAY RADIOISOTOPES</subject><subject>BETA-MINUS DECAY RADIOISOTOPES</subject><subject>BETA-PLUS DECAY RADIOISOTOPES</subject><subject>Biological and medical sciences</subject><subject>Brachytherapy</subject><subject>Brachytherapy - methods</subject><subject>CARCINOMAS</subject><subject>DAYS LIVING RADIOISOTOPES</subject><subject>DIGESTIVE SYSTEM</subject><subject>DISEASES</subject><subject>ELECTRON CAPTURE RADIOISOTOPES</subject><subject>Head and neck cancer</subject><subject>HEAVY NUCLEI</subject><subject>Humans</subject><subject>IMPLANTS</subject><subject>INTERNAL CONVERSION RADIOISOTOPES</subject><subject>Interstitial implants</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>IRIDIUM 192</subject><subject>IRIDIUM ISOTOPES</subject><subject>Iridium Radioisotopes - therapeutic use</subject><subject>ISOMERIC TRANSITION</subject><subject>ISOTOPES</subject><subject>Medical sciences</subject><subject>MEDICINE</subject><subject>Mouth Floor</subject><subject>Mouth Neoplasms - radiotherapy</subject><subject>NEOPLASMS</subject><subject>NUCLEAR MEDICINE</subject><subject>NUCLEI</subject><subject>ORAL CAVITY</subject><subject>PLANNING</subject><subject>RADIATION SOURCE IMPLANTS</subject><subject>RADIATION SOURCES</subject><subject>RADIOISOTOPES</subject><subject>RADIOLOGY</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy Planning, Computer-Assisted</subject><subject>THERAPY</subject><subject>Tongue Neoplasms - radiotherapy</subject><issn>0360-3016</issn><issn>1879-355X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kM2KFDEUhYMoYzv6BgqFiDiLGvNbVXEhyKBjQ8NsRnAXUsktJ1KVtEmqYd7exG566SqXnO9ezjkIvSb4mmDSfcSswy0r0wdJriSmeGh3T9CGDL1smRA_n6LNGXmOXqT0G2NMSM8v0AXFlAosN0hvfYaYsstOz802tkTSxi37WfucmjA1-QGaEItm9MHlx0_Nffmosnf-V6O9bUzwKcfVZBd83TiEeV3gfOQlejbpOcGr03uJfnz7en_zvd3d3W5vvuxawwnL7SiZxD23o7ZScy763naDZQDMCjt04yQmPNHe0kHjTjJqhTQw9j0zMDAgHbtEb493Q0mjknEZzEPx5sFkJXrGJavQ-yO0j-HPCimrxSUDc3EKYU1qwIIJzGkB-RE0MaQUYVL76BYdHxXBqtavareqdqskUf_qV7uy9uZ0fx0XsOelU99Ff3fSdTJ6nqL2xqUzJhinsqs2Px8xKIUdHMSaB7wB62KNY4P7v4-_4--gkg</recordid><startdate>19910501</startdate><enddate>19910501</enddate><creator>Schmidt-Ullrich, R.</creator><creator>Zwicker, R.D.</creator><creator>Wu, A.</creator><creator>Kelly, Kathleen</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>OTOTI</scope></search><sort><creationdate>19910501</creationdate><title>Interstitial Ir-192 implants of the oral cavity: The planning and construction of volume implants</title><author>Schmidt-Ullrich, R. ; Zwicker, R.D. ; Wu, A. ; Kelly, Kathleen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c413t-b939074dbad9a44577d68d3ee3d5d86bf5f0f27d28a06932d59ceb773ce83e163</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>550603 - Medicine- External Radiation in Therapy- (1980-)</topic><topic>BETA DECAY RADIOISOTOPES</topic><topic>BETA-MINUS DECAY RADIOISOTOPES</topic><topic>BETA-PLUS DECAY RADIOISOTOPES</topic><topic>Biological and medical sciences</topic><topic>Brachytherapy</topic><topic>Brachytherapy - methods</topic><topic>CARCINOMAS</topic><topic>DAYS LIVING RADIOISOTOPES</topic><topic>DIGESTIVE SYSTEM</topic><topic>DISEASES</topic><topic>ELECTRON CAPTURE RADIOISOTOPES</topic><topic>Head and neck cancer</topic><topic>HEAVY NUCLEI</topic><topic>Humans</topic><topic>IMPLANTS</topic><topic>INTERNAL CONVERSION RADIOISOTOPES</topic><topic>Interstitial implants</topic><topic>Investigative techniques, diagnostic techniques (general aspects)</topic><topic>IRIDIUM 192</topic><topic>IRIDIUM ISOTOPES</topic><topic>Iridium Radioisotopes - therapeutic use</topic><topic>ISOMERIC TRANSITION</topic><topic>ISOTOPES</topic><topic>Medical sciences</topic><topic>MEDICINE</topic><topic>Mouth Floor</topic><topic>Mouth Neoplasms - radiotherapy</topic><topic>NEOPLASMS</topic><topic>NUCLEAR MEDICINE</topic><topic>NUCLEI</topic><topic>ORAL CAVITY</topic><topic>PLANNING</topic><topic>RADIATION SOURCE IMPLANTS</topic><topic>RADIATION SOURCES</topic><topic>RADIOISOTOPES</topic><topic>RADIOLOGY</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy Planning, Computer-Assisted</topic><topic>THERAPY</topic><topic>Tongue Neoplasms - radiotherapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schmidt-Ullrich, R.</creatorcontrib><creatorcontrib>Zwicker, R.D.</creatorcontrib><creatorcontrib>Wu, A.</creatorcontrib><creatorcontrib>Kelly, Kathleen</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>OSTI.GOV</collection><jtitle>International journal of radiation oncology, biology, physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schmidt-Ullrich, R.</au><au>Zwicker, R.D.</au><au>Wu, A.</au><au>Kelly, Kathleen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Interstitial Ir-192 implants of the oral cavity: The planning and construction of volume implants</atitle><jtitle>International journal of radiation oncology, biology, physics</jtitle><addtitle>Int J Radiat Oncol Biol Phys</addtitle><date>1991-05-01</date><risdate>1991</risdate><volume>20</volume><issue>5</issue><spage>1079</spage><epage>1085</epage><pages>1079-1085</pages><issn>0360-3016</issn><eissn>1879-355X</eissn><coden>IOBPD3</coden><abstract>The success of radioactive implant therapy for head and neck carcinomas depends critically on careful planning and execution of the implant procedure. In this paper we discuss our experience with oral tongue and floor of mouth implants, and some innovations introduced to facilitate these procedures. Implants were carried out using standard angiocatheters modified with magnetic caps at the open end and terminated with Teflon spacers and lead shot at the closed end. The importance of accurate source placement and careful determination of the target dose rate is discussed with numerical examples. Differential hot-loading of sources is clearly indicated in cases of extension of the lesion to the dorsal or lateral tongue surface. For dorsal surface extension the use of Teflon spacers at the closed ends of the catheters helps to ensure adequate coverage of the target volume with the higher dose region enclosing the demonstrable tumor. All 10 patients implanted with this technique are controlled without recurrence at a median follow-up of 38 months. The two complications observed appeared to be associated with excessive hot-loading of edge plane sources.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>2022509</pmid><doi>10.1016/0360-3016(91)90208-L</doi><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0360-3016 |
| ispartof | International journal of radiation oncology, biology, physics, 1991-05, Vol.20 (5), p.1079-1085 |
| issn | 0360-3016 1879-355X |
| language | eng |
| recordid | cdi_osti_scitechconnect_5734936 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | 550603 - Medicine- External Radiation in Therapy- (1980-) BETA DECAY RADIOISOTOPES BETA-MINUS DECAY RADIOISOTOPES BETA-PLUS DECAY RADIOISOTOPES Biological and medical sciences Brachytherapy Brachytherapy - methods CARCINOMAS DAYS LIVING RADIOISOTOPES DIGESTIVE SYSTEM DISEASES ELECTRON CAPTURE RADIOISOTOPES Head and neck cancer HEAVY NUCLEI Humans IMPLANTS INTERNAL CONVERSION RADIOISOTOPES Interstitial implants Investigative techniques, diagnostic techniques (general aspects) IRIDIUM 192 IRIDIUM ISOTOPES Iridium Radioisotopes - therapeutic use ISOMERIC TRANSITION ISOTOPES Medical sciences MEDICINE Mouth Floor Mouth Neoplasms - radiotherapy NEOPLASMS NUCLEAR MEDICINE NUCLEI ORAL CAVITY PLANNING RADIATION SOURCE IMPLANTS RADIATION SOURCES RADIOISOTOPES RADIOLOGY RADIOLOGY AND NUCLEAR MEDICINE RADIOTHERAPY Radiotherapy Planning, Computer-Assisted THERAPY Tongue Neoplasms - radiotherapy |
| title | Interstitial Ir-192 implants of the oral cavity: The planning and construction of volume implants |
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