The Genetic Basis of Strain-Dependent Differences in the Early Phase of Radiation Injury in Mouse Lung

Substantial differences between mouse strains have been reported in the lesions present in the lung during the early phase of radiation injury. Some strains show only classical pneumonitis, while other strains develop substantial fibrosis and hyaline membranes which contribute appreciably to respira...

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Veröffentlicht in:	Radiation research 1991-06, Vol.126 (3), p.349-356
Hauptverfasser:	Franko, Allan J., Sharplin, Janet, Ward, William F., Hinz, Joann M.
Format:	Artikel
Sprache:	eng
Schlagworte:	560152 - Radiation Effects on Animals- Animals ANIMALS Biological and medical sciences BIOLOGICAL EFFECTS Biological effects of radiation BIOLOGICAL RADIATION EFFECTS BIOLOGICAL VARIABILITY BODY DISEASES Female FIBROSIS Fundamental and applied biological sciences. Psychology GENETIC VARIABILITY Hyalin Hybridity INJURIES Ionizing radiations Irradiation Lesions Lung - enzymology Lung - pathology Lung - radiation effects LUNGS Male MAMMALS MICE Mice, Inbred Strains - genetics ORGANS PATHOLOGICAL CHANGES Peptidyl-Dipeptidase A - metabolism Plasminogen Activators - metabolism RADIATION EFFECTS Radiation genetics RADIATION INJURIES Radiation Injuries, Experimental - enzymology Radiation Injuries, Experimental - genetics Radiation Injuries, Experimental - pathology RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOINDUCTION RESPIRATORY SYSTEM RESPIRATORY SYSTEM DISEASES RODENTS Species Specificity Sprains and strains Tissues, organs and organisms biophysics VERTEBRATES
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