Estimates of Beta Absorbed Fractions in Small Tissue Volumes for Selected Radionuclides
Energy deposition patterns are dependent upon the size and geometry of the source region, distribution of radioactive material, types of radiations and energies emitted by the radionuclide, as well as interfaces between different materials which may exist within the region. Commonly, in absorbed dos...
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| Veröffentlicht in: | The Journal of nuclear medicine (1978) 1991-05, Vol.32 (5), p.835-839 |
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| container_title | The Journal of nuclear medicine (1978) |
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| creator | Akabani, Gamal Poston, John W., Sr Bolch, Wesley E |
| description | Energy deposition patterns are dependent upon the size and geometry of the source region, distribution of radioactive material, types of radiations and energies emitted by the radionuclide, as well as interfaces between different materials which may exist within the region. Commonly, in absorbed dose calculations for internally deposited beta-emitting radionuclides, it is assumed that the absorbed fraction of energy for the mean beta energy is a sufficient representation of the beta spectrum. The accuracy of this assumption was tested by comparing absorbed fractions calculated using actual beta spectral energies with those obtained using the mean beta energy for several radionuclides commonly used in nuclear medicine. A sphere composed of tissue was chosen as the preferred geometry. Spheres of 0.1, 0.5, 1.0, and 2.0 cm radius were used, and absorbed fractions were calculated as a function of surface-to-volume ratios. This allows the assessment of absorbed fraction in spheres where there is a uniform distribution of a radionuclide. |
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Commonly, in absorbed dose calculations for internally deposited beta-emitting radionuclides, it is assumed that the absorbed fraction of energy for the mean beta energy is a sufficient representation of the beta spectrum. The accuracy of this assumption was tested by comparing absorbed fractions calculated using actual beta spectral energies with those obtained using the mean beta energy for several radionuclides commonly used in nuclear medicine. A sphere composed of tissue was chosen as the preferred geometry. Spheres of 0.1, 0.5, 1.0, and 2.0 cm radius were used, and absorbed fractions were calculated as a function of surface-to-volume ratios. This allows the assessment of absorbed fraction in spheres where there is a uniform distribution of a radionuclide.</description><identifier>ISSN: 0161-5505</identifier><identifier>EISSN: 1535-5667</identifier><identifier>PMID: 2022992</identifier><language>eng</language><publisher>Reston, VA: Soc Nuclear Med</publisher><subject>560161 - Radionuclide Effects, Kinetics, & Toxicology- Man ; ANIMAL TISSUES ; BETA PARTICLES ; Biological and medical sciences ; BODY ; CHARGED PARTICLES ; DOSES ; FRACTIONATED IRRADIATION ; Humans ; Investigative techniques, diagnostic techniques (general aspects) ; IRRADIATION ; ISOTOPES ; Medical sciences ; MEDICINE ; Models, Theoretical ; MONTE CARLO METHOD ; NUCLEAR MEDICINE ; RADIATION DOSES ; RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. 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Commonly, in absorbed dose calculations for internally deposited beta-emitting radionuclides, it is assumed that the absorbed fraction of energy for the mean beta energy is a sufficient representation of the beta spectrum. The accuracy of this assumption was tested by comparing absorbed fractions calculated using actual beta spectral energies with those obtained using the mean beta energy for several radionuclides commonly used in nuclear medicine. A sphere composed of tissue was chosen as the preferred geometry. Spheres of 0.1, 0.5, 1.0, and 2.0 cm radius were used, and absorbed fractions were calculated as a function of surface-to-volume ratios. This allows the assessment of absorbed fraction in spheres where there is a uniform distribution of a radionuclide.</description><subject>560161 - Radionuclide Effects, Kinetics, & Toxicology- Man</subject><subject>ANIMAL TISSUES</subject><subject>BETA PARTICLES</subject><subject>Biological and medical sciences</subject><subject>BODY</subject><subject>CHARGED PARTICLES</subject><subject>DOSES</subject><subject>FRACTIONATED IRRADIATION</subject><subject>Humans</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>IRRADIATION</subject><subject>ISOTOPES</subject><subject>Medical sciences</subject><subject>MEDICINE</subject><subject>Models, Theoretical</subject><subject>MONTE CARLO METHOD</subject><subject>NUCLEAR MEDICINE</subject><subject>RADIATION DOSES</subject><subject>RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. 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POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. 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Commonly, in absorbed dose calculations for internally deposited beta-emitting radionuclides, it is assumed that the absorbed fraction of energy for the mean beta energy is a sufficient representation of the beta spectrum. The accuracy of this assumption was tested by comparing absorbed fractions calculated using actual beta spectral energies with those obtained using the mean beta energy for several radionuclides commonly used in nuclear medicine. A sphere composed of tissue was chosen as the preferred geometry. Spheres of 0.1, 0.5, 1.0, and 2.0 cm radius were used, and absorbed fractions were calculated as a function of surface-to-volume ratios. This allows the assessment of absorbed fraction in spheres where there is a uniform distribution of a radionuclide.</abstract><cop>Reston, VA</cop><pub>Soc Nuclear Med</pub><pmid>2022992</pmid><tpages>5</tpages></addata></record> |
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| ispartof | The Journal of nuclear medicine (1978), 1991-05, Vol.32 (5), p.835-839 |
| issn | 0161-5505 1535-5667 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | 560161 - Radionuclide Effects, Kinetics, & Toxicology- Man ANIMAL TISSUES BETA PARTICLES Biological and medical sciences BODY CHARGED PARTICLES DOSES FRACTIONATED IRRADIATION Humans Investigative techniques, diagnostic techniques (general aspects) IRRADIATION ISOTOPES Medical sciences MEDICINE Models, Theoretical MONTE CARLO METHOD NUCLEAR MEDICINE RADIATION DOSES RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOISOTOPES Radiometry - methods Radionuclide investigations TISSUES |
| title | Estimates of Beta Absorbed Fractions in Small Tissue Volumes for Selected Radionuclides |
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