A Quantitative Histological Study of Strain-Dependent Differences in the Effects of Irradiation on Mouse Lung during the Intermediate and Late Phases

Strain differences in the intermediate and late phases of the radiation response of mouse lung were investigated histologically. The proportion of lung impairment in mice at 28 and 52 weeks postirradiation and in mice dying of respiratory insufficiency was assessed by scoring lung acini as nonfuncti...

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Veröffentlicht in:	Radiation research 1989-07, Vol.119 (1), p.15-31
Hauptverfasser:	Sharplin, Janet, Franko, Allan J.
Format:	Artikel
Sprache:	eng
Schlagworte:	560152 - Radiation Effects on Animals- Animals ANIMALS Biological and medical sciences BIOLOGICAL EFFECTS Biological effects of radiation BIOLOGICAL RADIATION EFFECTS BIOLOGICAL VARIABILITY BLOOD FLOW BODY FIBROSIS Fundamental and applied biological sciences. Psychology GENETIC VARIABILITY Histology Hyalin Ionizing radiations Irradiation Lesions Lung - pathology Lung - radiation effects LUNGS MAMMALS MICE Mice, Inbred Strains ORGANS PATHOLOGICAL CHANGES PERFUSED ORGANS Perfusion Pleural effusion Pleural Effusion - etiology Pleural Effusion - pathology Pulmonary alveoli Pulmonary Fibrosis - etiology Pulmonary Fibrosis - mortality Pulmonary Fibrosis - pathology Radiation damage RADIATION EFFECTS RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT Respiratory Insufficiency - etiology Respiratory Insufficiency - mortality Respiratory Insufficiency - pathology RESPIRATORY SYSTEM RODENTS Space life sciences Species Specificity Time Factors Tissues, organs and organisms biophysics VERTEBRATES
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